Wellmedr vs DirectMeds: NAD+ Therapy Compared
Wellmedr starts at $99 and offers injection, while DirectMeds starts at $99 first month (500mg) with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
Wellmedr
Starting at $99 — Physician-supervised NAD+ injections. No memberships. Free shipping.
Visit Wellmedr →
DirectMeds
Save $100 first month — 500mg from $99, then $199. 250,000+ served. No subscription.
Visit DirectMeds →| Feature | Wellmedr | DirectMeds |
|---|---|---|
| Editorial score | 9.78 / 10 | 9.64 / 10 |
| Starting price | $99 | $99 first month (500mg) |
| Renewal / ongoing | Same price at every dose | $199 (500mg) / $249 (1000mg) |
| Delivery formats | Injection | Injection |
| Dose strengths | 500mg & 1000mg | 500mg & 1000mg |
| Shipping | Free 1–2 day | Free 1–2 day |
| Membership / fees | None | None — no subscription |
| Guarantee | — | Satisfaction guarantee |
| Best for | People seeking affordable physician-supervised NAD+ therapy without memberships or hidden fees | People who want exact upfront pricing and no forced subscription, reordering on their own schedule |
Where Wellmedr stands out
- + Higher editorial score (9.78 vs 9.64)
Where DirectMeds stands out
- + Backed by a satisfaction guarantee
Pros & cons, side by side
Wellmedr
Pros
- + Starts at $99 — one of the most accessible entry prices
- + Online consultation and prescription management included
- + No monthly membership or recurring commitments required
- + Free shipping on every order
- + 500mg and 1000mg dosage options available
- + Typically ships 1-2 days after approval
Cons
- − Newer platform with a smaller patient base
- − Limited public reviews compared to established providers
DirectMeds
Pros
- + $100 off first month on the 500mg plan
- + Exact pricing shown upfront for both 500mg and 1000mg
- + No forced subscription — reorder manually when you want
- + 1:1 medical support with provider review within 24 hours
- + Free 1–2 day shipping included
Cons
- − Injection-only — no nasal or oral option
- − 1000mg plan renews at $249/mo
The verdict: Wellmedr vs DirectMeds
In our editorial ranking, Wellmedr places higher (#2 vs #5), making it the default pick for most readers — it's best for people seeking affordable physician-supervised NAD+ therapy without memberships or hidden fees. That said, DirectMeds is the stronger choice for people who want exact upfront pricing and no forced subscription, reordering on their own schedule. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.