DirectMeds vs Eden: NAD+ Therapy Compared
DirectMeds starts at $99 first month (500mg) and offers injection, while Eden starts at $119 first month (~$15/shot) with injection (+ separate nasal spray). Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
DirectMeds
Save $100 first month — 500mg from $99, then $199. 250,000+ served. No subscription.
Visit DirectMeds →
Eden
NAD+ from $119 first month (~$15/shot). FSA/HSA eligible. Klarna & Afterpay available.
Visit Eden →| Feature | DirectMeds | Eden |
|---|---|---|
| Editorial score | 9.64 / 10 | 8.27 / 10 |
| Starting price | $99 first month (500mg) | $119 first month (~$15/shot) |
| Renewal / ongoing | $199 (500mg) / $249 (1000mg) | Medication + $99/mo membership |
| Delivery formats | Injection | Injection (+ separate nasal spray) |
| Dose strengths | 500mg & 1000mg | 500–1000mg at 200mg/mL |
| Shipping | Free 1–2 day | Free 2-day + home kit |
| Membership / fees | None — no subscription | $39 then $99/mo (required) |
| Guarantee | Satisfaction guarantee | — |
| Best for | People who want exact upfront pricing and no forced subscription, reordering on their own schedule | People who want flexible financing and FSA/HSA payment for physician-supervised NAD+ |
Where DirectMeds stands out
- + Lower entry price — $99 first month (500mg)
- + No required membership fee
- + Backed by a satisfaction guarantee
- + Higher editorial score (9.64 vs 8.27)
Where Eden stands out
- + More delivery formats — injection (+ separate nasal spray)
Pros & cons, side by side
DirectMeds
Pros
- + $100 off first month on the 500mg plan
- + Exact pricing shown upfront for both 500mg and 1000mg
- + No forced subscription — reorder manually when you want
- + 1:1 medical support with provider review within 24 hours
- + Free 1–2 day shipping included
Cons
- − Injection-only — no nasal or oral option
- − 1000mg plan renews at $249/mo
Eden
Pros
- + Low ~$15-per-shot framing with free 2-day shipping and home kit
- + FSA/HSA eligible
- + Pay over time with Klarna or Afterpay
- + 500–1000mg injections plus a separate nasal spray option
Cons
- − Requires an Eden membership ($39 first month, then $99/mo) on top of medication
- − Compounded NAD+ — not an FDA-approved finished product
The verdict: DirectMeds vs Eden
In our editorial ranking, DirectMeds places higher (#5 vs #14), making it the default pick for most readers — it's best for people who want exact upfront pricing and no forced subscription, reordering on their own schedule. That said, Eden is the stronger choice for people who want flexible financing and FSA/HSA payment for physician-supervised NAD+. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.