DirectMeds vs Sprout Health: NAD+ Therapy Compared
DirectMeds starts at $99 first month (500mg) and offers injection, while Sprout Health starts at $149 first month with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
DirectMeds
Save $100 first month — 500mg from $99, then $199. 250,000+ served. No subscription.
Visit DirectMeds →
Sprout Health
Transparent dosing — 1,000mg/5mL twice weekly. $149 first month, then $240 every 4 weeks.
Visit Sprout Health →| Feature | DirectMeds | Sprout Health |
|---|---|---|
| Editorial score | 9.64 / 10 | 8.76 / 10 |
| Starting price | $99 first month (500mg) | $149 first month |
| Renewal / ongoing | $199 (500mg) / $249 (1000mg) | $240 every 4 weeks |
| Delivery formats | Injection | Injection |
| Dose strengths | 500mg & 1000mg | 1,000mg/5mL, twice weekly |
| Shipping | Free 1–2 day | Free & discreet |
| Membership / fees | None — no subscription | None |
| Guarantee | Satisfaction guarantee | No charge if clinician declines |
| Best for | People who want exact upfront pricing and no forced subscription, reordering on their own schedule | People who want full upfront disclosure of dose, frequency, and renewal price before starting |
Where DirectMeds stands out
- + Lower entry price — $99 first month (500mg)
- + Higher editorial score (9.64 vs 8.76)
Where Sprout Health stands out
Sprout Health is closely matched with DirectMeds on the headline metrics — the deciding factors come down to delivery format and the specifics below.
Pros & cons, side by side
DirectMeds
Pros
- + $100 off first month on the 500mg plan
- + Exact pricing shown upfront for both 500mg and 1000mg
- + No forced subscription — reorder manually when you want
- + 1:1 medical support with provider review within 24 hours
- + Free 1–2 day shipping included
Cons
- − Injection-only — no nasal or oral option
- − 1000mg plan renews at $249/mo
Sprout Health
Pros
- + Fully discloses vial strength, dosing frequency, and renewal price
- + Free consultation, injection kit, and discreet shipping included
- + No hidden fees and cancel anytime
Cons
- − Renews at $240 every 4 weeks — higher than many competitors
- − Injection-only; not available in AR, KS, or NM
The verdict: DirectMeds vs Sprout Health
In our editorial ranking, DirectMeds places higher (#5 vs #12), making it the default pick for most readers — it's best for people who want exact upfront pricing and no forced subscription, reordering on their own schedule. That said, Sprout Health is the stronger choice for people who want full upfront disclosure of dose, frequency, and renewal price before starting. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.