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DirectMeds vs Wellmedr: NAD+ Therapy Compared

DirectMeds starts at $99 first month (500mg) and offers injection, while Wellmedr starts at $99 with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.

Our #2 pick
DirectMeds logo

DirectMeds

9.64

Save $100 first month — 500mg from $99, then $199. 250,000+ served. No subscription.

Visit DirectMeds
VS
Our #4 pick
Wellmedr logo

Wellmedr

9.78

This provider offer is currently unavailable. See other NAD+ providers below for active options.

Visit Wellmedr
FeatureDirectMedsWellmedr
Editorial score9.64 / 109.78 / 10
Starting price$99 first month (500mg)$99
Renewal / ongoing$199 (500mg) / $249 (1000mg)Same price at every dose
Delivery formatsInjectionInjection
Dose strengths500mg & 1000mg500mg & 1000mg
ShippingFree 1–2 dayFree 1–2 day
Membership / feesNone — no subscriptionNone
GuaranteeSatisfaction guarantee
Best forPeople who want exact upfront pricing and no forced subscription, reordering on their own schedulePreviously a good fit for accessible physician-supervised NAD+ — currently unavailable

Where DirectMeds stands out

  • + Backed by a satisfaction guarantee

Where Wellmedr stands out

  • + Higher editorial score (9.78 vs 9.64)

Pros & cons, side by side

DirectMeds

Pros

  • + $100 off first month on the 500mg plan
  • + Exact pricing shown upfront for both 500mg and 1000mg
  • + No forced subscription — reorder manually when you want
  • + 1:1 medical support with provider review within 24 hours
  • + Free 1–2 day shipping included

Cons

  • Injection-only — no nasal or oral option
  • 1000mg plan renews at $249/mo

Wellmedr

Pros

  • + Physician-supervised NAD+ injections
  • + Online consultation and prescription management
  • + 500mg and 1000mg dosage options

Cons

  • Offer is currently unavailable

The verdict: DirectMeds vs Wellmedr

In our editorial ranking, DirectMeds places higher (#2 vs #4), making it the default pick for most readers — it's best for people who want exact upfront pricing and no forced subscription, reordering on their own schedule. That said, Wellmedr is the stronger choice for previously a good fit for accessible physician-supervised NAD+ — currently unavailable. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.

Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.