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NAD+ Treatment Cost

  • Physician-prescribed only
  • FSA/HSA Eligible

01

DirectMeds

DirectMeds logo

NAD+ From $79, Straight From Own Pharmacy

  • Same price, every dose. No hidden fees
  • 100% Online & Safe
9.83OutstandingEditorial score
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Get Started from $79

Editor's pick · Reviewed November 2026

02

BettermeRx

BettermeRx logo

NAD+ From $99, Injection or Nasal Spray

  • Two formats, flat pricing
  • Shipped straight to your door
9.97OutstandingEditorial score
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Get Started from $99

DirectMeds logo

NAD+ From $79, Straight From Own Pharmacy

Our #1 pick · Get started from $79

03

System

System logo

NAD+ From $69, Injection or Nasal

  • Nasal spray from $69 first month
  • Injection from $89 first month
9.68ExcellentEditorial score
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Get Started from $69

04

Lttl

Lttl logo

NAD+ Starting at $99

  • 100% online, three formats available
  • Free shipping, arrives in 1–2 days
9.91OutstandingEditorial score
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Get Started from $99

05

AgelessRx

AgelessRx logo

NAD+ From $79, Save Up to $70

  • Under $3/day on the 3-month plan
  • Pause or cancel anytime
9.76ExcellentEditorial score
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Get Started from $79

06

bmiMD

bmiMD logo

NAD+ Injections From $89/mo

  • One of the lowest prices we track
  • Visit and consult included
9.59ExcellentEditorial score
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Get Started from $89

07

ReadyRx

ReadyRx logo

Lab-Tested NAD+ From $84

  • Online evaluation included
  • Quarterly plan saves money
9.52ExcellentEditorial score
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Get Started from $84

Best Overall Pick

01

DirectMeds

DirectMeds logo

NAD+ From $79, Straight From Own Pharmacy

  • Same price, every dose. No hidden fees
  • 100% Online & Safe
9.83OutstandingEditorial score
Visit Site

Get Started from $79

Editor's pick · Reviewed November 2026
How We RankOnly figures a provider publishes on its own site.No clinical testing and no patient outcome data.Unverifiable numbers are shown as “not published”.Rankings are editorial, not paid placement.

Top-rated NAD+ providers

Our three highest-rated providers, before the full cost breakdown below. If price is the deciding factor, DirectMeds publishes the lowest entry price at $79/mo (list $199/mo), the cheapest NAD+ providers page ranks them with the conditions attached.

Average monthly NAD+ cost

The honest headline number is a range, not an average: $79 to $249 a month depending on format, quantity and how long you commit for. The median published entry price across providers is about $134. Most people comparing injection plans will end up choosing between something in the $99–$199 band.

Lowest published price
$79/month, DirectMeds
Median published price
About $134/month
Highest published price
About $249/month
Typical injection plan
$99–$199/month
Typical nasal spray plan
$69–$169/month
Consultation
Included at every provider we track
Shipping
Free at every provider that publishes a policy

Provider price comparison

Every provider with a published price, cheapest first, with the renewal rate beside it. The gap between those two columns is where most people get caught out.

ProviderStarting priceRenews at
DirectMeds$79/mo (list $199/mo)Rate locked at sign-up; same price at every dose
ReadyRxFrom $84Same price at every dose
Enhance MDWafers $84/mo; injection $169/moWafers $84–$99; injection $169–$199
SystemInjection $89 · nasal $69 (first month)Shown during intake
bmiMD$89/moPrice-locked at $89/mo
Embody$99Varies by plan
Wellmedr$99Same price at every dose
Remote Pharmacy$99Varies by dose
Eden$119 first month (~$15/shot)Medication + $99/mo membership
RNK Health$129/mo$129/mo
Enhanced.com$139/mo (was $232, save 40%)$129–$149/mo by plan length
Shed$144/mo nasal (20% off first month)$144 nasal / $169 injection & oral
He & She MD$149/mo (12-month supply)Flat $149/mo across every format
Sprout Health$149 first month$240 every 4 weeks
Tmates$149/mo (as low as ~$88 on longer plans)From ~$88/mo on longer plans
Wellorithm~$150 first month~$200/mo regular
RenuviaRX$179 to start$249/mo
Fridays$179/mo (billed quarterly)Nasal & oral $229/mo
CareBareRx$199/mo$199/mo
RXSpan~$249 (recurring)Recurring; shown before checkout

Two provider prices are not on this table because they are not published before intake: BetterMeRx shows your price after a free online evaluation, and ReadyRx shows live pricing once you start the intake. That is a real cost of comparison, and it is reflected in our pricing-transparency scoring.

NAD+ injection prices

Injection plans are the bulk of the market, 18 of the 29 providers we track sell one. Entry prices among them start at $84 and run to roughly $249.

  • DirectMeds: $79/mo (list $199/mo), renewing at Rate locked at sign-up; same price at every dose.
  • BettermeRx: Shown after free evaluation, renewing at Flat pricing, no increases.
  • System: Injection $89 · nasal $69 (first month), renewing at Shown during intake.
  • Lttl: From $99, renewing at a rate not disclosed.
  • bmiMD: $89/mo, renewing at Price-locked at $89/mo.
  • ReadyRx: From $84, renewing at Same price at every dose.
  • Enhanced.com: $139/mo (was $232, save 40%), renewing at $129–$149/mo by plan length.
  • Embody: $99, renewing at Varies by plan.
  • Wellmedr: $99, renewing at Same price at every dose.
  • Remote Pharmacy: $99, renewing at Varies by dose.

NAD+ nasal spray prices

Nasal spray is usually priced at or below the injection plan at the same provider. System is the cheapest entry point, selling nasal at $69 for the first month against $89 for its injection. Shed prices nasal at $144/mo against $169 for injection and oral.

  • BettermeRx: Shown after free evaluation. Injection 500/1,000 mg; nasal 900 mg.
  • System: Injection $89 · nasal $69 (first month). Not disclosed.
  • Lttl: From $99. Same price at every dose; strength not disclosed.
  • bmiMD: $89/mo. Nasal 300 mg/mL; injection per protocol.
  • ReadyRx: From $84. Injection 500/1,000 mg; nasal 4,500 mg.
  • Embody: $99. 500 mg and 1,000 mg vials.
  • He & She MD: $149/mo (12-month supply). Supplied as a 12-month course.
  • Fridays: $179/mo (billed quarterly). Oral 50/100/150 mg daily; injection 3×/week.
  • RNK Health: $129/mo. Clinician-titrated.
  • Shed: $144/mo nasal (20% off first month). Provider-determined.

Medication quantity

A price only means something next to a quantity. Remote Pharmacy at $99 and CareBareRx at $199 are not comparable numbers if one publishes 500 mg and 1,000 mg vial options and the other publishes nothing at all. The providers that state quantity up front, Remote Pharmacy, DirectMeds, Wellmedr, Embody, BetterMeRx, ReadyRx, Eden and Sprout Health, are the ones you can actually price-check.

Sprout Health is the clearest of the group: 1,000 mg / 5 mL, twice weekly, published before enrolment, renewing at $240 every four weeks. You can calculate your cost per dose from that. At providers that publish no quantity, you cannot.

Consultation fees

Zero, everywhere. Every provider on this site bundles the online medical consultation into the plan price rather than charging for it separately. Several go further and remove the downside risk entirely: bmiMD refunds in full if you are not approved, Enhance MD refunds if you are found ineligible, Sprout Health does not charge if a clinician declines you, and Embody refunds if you are not eligible.

Shipping costs

Also zero at every provider that publishes a policy. Enhanced.com, Remote Pharmacy, DirectMeds and Wellmedr publish free 1–2 day shipping; Embody and Eden free 2-day; BetterMeRx free UPS/FedEx; bmiMD, ReadyRx and RenuviaRX free shipping; Sprout Health free and discreet; RNK Health included at roughly 48 hours; He & She MD free expedited. System, Tmates, RXSpan, Wellorithm and CareBareRx do not publish a shipping policy.

Injection supplies

Needles, syringes, alcohol wipes and sharps disposal are included at no extra charge at every injection provider that publishes what ships. Eden calls out a full home injection kit; Sprout Health includes the injection kit with its free consultation. Nobody in this comparison set charges separately for supplies, but where a provider does not publish what is in the box, budget for the possibility.

Initial versus recurring costs

This is the single most important distinction on this page. Several providers advertise a first-month price that is materially lower than what you pay from month two.

DirectMeds
Currently $79/mo against a $199/mo list price, same at every dose
Sprout Health
$149 first month → $240 every 4 weeks
Wellorithm
~$150 first month → ~$200/mo
Eden
$119 first month → medication plus $99/mo membership
RenuviaRX
$179 to start → $249/mo
System
Injection $89 / nasal $69 first month → shown during intake

Providers that hold a flat rate are worth noting for the opposite reason: He & She MD keeps $149/mo across every format, Wellmedr charges the same price at every dose, and RNK Health publishes $129/mo both to start and on renewal.

Monthly plans

Month-to-month is the most expensive way to buy NAD+ at almost every provider, and the most flexible. Enhanced.com is the clearest illustration: $149/month for a one-month supply against $129/month on the six-month plan. If you are trying treatment for the first time, that premium is the price of being able to walk away after four weeks, usually worth paying. bmiMD is the notable exception: its $89 is a price-locked monthly rate, so there is no month-to-month penalty to weigh.

Multi-month plans

Longer terms are where the advertised headline prices come from. Understand what you are locking into.

  • He & She MD: $149/mo is based on a 12-month supply.
  • bmiMD: a price-locked $89/mo with the provider visit included.
  • Enhanced.com: $139/mo standard, dropping to $129/mo on the 6-month plan.
  • Enhance MD: lowest rates require a 12-month prepaid commitment.
  • Tmates: $149/mo for one month, falling to roughly $88/mo on longer plans.
  • Fridays: $179/mo but billed quarterly, so the first charge covers three months.

Subscription requirements

If you do not want a recurring charge at all, the list is short: DirectMeds and Wellmedr both publish no subscription requirement, and Remote Pharmacy and BetterMeRx publish no membership requirement. Everywhere else, expect a recurring plan, and at Eden, expect a membership charge on top of the medication.

Cancellation charges

None of the providers we track publish an explicit cancellation fee, but two publish constraints that function like one. Shed requires you to complete at least two months before cancelling, so the real minimum spend is two months of plan cost. RNK Health does not refund once medication has shipped. On prepaid multi-month terms, cancelling early generally means forfeiting the discount you prepaid for, check the specific terms before committing to 12 months.

Hidden fees

  • Memberships. Eden charges $39 then $99/mo on top of medication. No other provider in this set does.
  • Renewal jumps. DirectMeds returns to its $199 list price when the $79 promotion ends, Sprout Health goes from $149 to $240, RenuviaRX from $179 to $249.
  • Prices only shown at intake. BetterMeRx, ReadyRx, System, RXSpan and Wellorithm reveal some or all pricing after you start the funnel.
  • Quarterly billing.Fridays' $179/mo is charged three months at a time.
  • Paid add-ons.Shed's 1:1 coaching costs extra on top of the plan.

Overall value

Best value overall goes to providers that hold one clear price with everything inside it. He & She MD's flat $149/mo across three formats with no membership is the cleanest deal in the set if you want format flexibility. Enhanced.com at $139/mo with a 90-day money-back guarantee carries the least downside risk. bmiMD at a price-locked $89/mo is the lowest genuine sustained cost. And DirectMeds is the best fit if you would rather pay $199 with no subscription at all than $99 with one.

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NAD+ treatment cost: frequently asked questions

Keep reading

Pricing and plan terms last verified August 2026. Provider terms change often, always confirm the current price, renewal rate and cancellation policy on the provider's own site before enrolling. We may earn a commission from partner links on this page, which never affects our rankings - see our disclosure. This page is informational and is not medical advice.

BestNADTreatments Editorial Team

Independent provider research and pricing analysis

Non-clinical editorial team, see our disclosure

Last Updated
November 2, 2026

This page is independent editorial research, not medical advice, and has not been reviewed by a licensed clinician. NAD+ requires evaluation by a licensed healthcare professional, and a prescription is not guaranteed. Discuss your health history, medications and treatment goals with a qualified clinician before starting any treatment.

Medical Disclaimer

The information on BestNADTreatments.com is provided for educational and comparison purposes only. It is not medical advice and does not replace consultation with a qualified healthcare professional. NAD+ treatment requires evaluation by a licensed clinician, and a prescription is not guaranteed. Compounded medications are not FDA-approved, and treatment availability varies by state and provider.

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Medical disclaimer: This page is for informational purposes only and is not medical advice. Always consult a licensed healthcare provider before starting any NAD+ therapy. We may earn a commission from partner links on this page - see our affiliate disclosure.