DirectMeds NAD+ Review 2026: $99 First Month, No Subscription
- Physician-prescribed only
- 30 providers compared
DirectMeds sells NAD+ injections with one idea at the centre: the price you pay covers everything. Medication, the doctor review, pharmacy compounding, supplies and shipping are bundled, and there is no subscription to escape. The first month is discounted to $99 on the 500mg plan. After that it is $199, which is not the cheapest NAD+ around, but it is predictable.
What Is DirectMeds?
DirectMeds is a telehealth pharmacy service. You answer a short health qualifier online, which takes about a minute, pick a prescription, and have a telehealth visit the same day. A licensed provider reviews your chart before anything ships.
It is injection-only, so there is no nasal spray or oral option. If you want a choice of format, our guide to NAD+ injections online lists the providers that sell more than one.
Doses and Pricing
Two strengths are available. The 500mg plan costs $99 for the first month after a $100 discount, then $199 a month. The 1,000mg plan costs $180 for the first month after a $69 discount, then $249 a month. DirectMeds describes its standard protocol as 1,000mg depending on weight and tolerance, taken once a day for five days a week.
The first-month discount matters because the renewal price is the real price. Budget for $199 or $249, then compare it with the options in our NAD+ treatment cost guide.
Check DirectMeds Pricing →How the Process Works
- 1
Health qualifier. About a minute online.
- 2
Choose and pay. Select your prescription and pay.
- 3
Telehealth visit. Happens the same day.
- 4
Provider review. DirectMeds says within 24 hours, and often under 5 hours.
- 5
Shipment. The pharmacy ships by one-day FedEx or UPS, and delivery takes one to two days.
Pharmacy, Terms and Guarantees
The medication is dispensed by U.S.-based 503B compounding pharmacies, which DirectMeds describes as FDA-registered facilities. Month-to-month pricing has no contract, and you can cancel by email or phone.
If you are not approved for the prescription, you get a full refund. A patient satisfaction guarantee also applies. DirectMeds ships to every US state except Mississippi.
See If DirectMeds Ships to You →Pros and Cons
Pros
- + Everything is included: medication, review, supplies and shipping
- + Same-day telehealth visit and a fast provider review
- + Full refund if you are not approved
- + No contract and cancellation by email or phone
- + 503B US compounding pharmacies
Cons
- − Injection only, with no nasal or oral option
- − 500mg renews at $199 and 1,000mg at $249 after the first month
- − Not available in Mississippi
DirectMeds vs Alternatives
DirectMeds is stronger on speed and inclusions than on price. The AgelessRx review shows the trade-off: a lower introductory rate but slower delivery. If you would rather choose between an injection and a spray, see BettermeRx vs DirectMeds.
Verdict
DirectMeds is a good fit if you want NAD+ injections quickly, with a clear all-in price, a refund if you are not approved, and nothing to cancel. It is less attractive if you want a lower ongoing monthly cost or a needle-free option.
Get Started with DirectMeds →DirectMeds NAD+ FAQ
How much does DirectMeds NAD+ cost?
The 500mg plan is $99 for the first month after a $100 discount, then $199 a month. The 1,000mg plan is $180 for the first month after a $69 discount, then $249 a month.
What does the DirectMeds price include?
Medication, doctor review, pharmacy compounding, supplies and 2-day shipping. DirectMeds states there are no subscriptions or hidden fees.
What if I am not approved?
DirectMeds offers a full refund if your prescription is not approved, plus a patient satisfaction guarantee.
Where does DirectMeds ship?
It serves all US states except Mississippi.
Disclosure: This page contains affiliate links. BestNadTreatments.com may earn a commission at no extra cost to you if you purchase through them. Pricing, features and offers are subject to change; verify current details on the official DirectMeds website. Rx required. A licensed healthcare professional will determine if treatment is appropriate for you. Compounded NAD+ is not an FDA-approved finished product, and NAD+ therapy is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary.
Independent provider research and pricing analysis
Non-clinical editorial team, see our disclosure
This page is independent editorial research, not medical advice, and has not been reviewed by a licensed clinician. NAD+ requires evaluation by a licensed healthcare professional, and a prescription is not guaranteed. Discuss your health history, medications and treatment goals with a qualified clinician before starting any treatment.
Medical Disclaimer
The information on BestNADTreatments.com is provided for educational and comparison purposes only. It is not medical advice and does not replace consultation with a qualified healthcare professional. NAD+ treatment requires evaluation by a licensed clinician, and a prescription is not guaranteed. Compounded medications are not FDA-approved, and treatment availability varies by state and provider.
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