Enhanced.com vs He & She MD: NAD+ Therapy Compared
- Physician-prescribed only
- 31 providers compared
Enhanced.com
Enhanced delivers NAD+Rx restored to clinical levels through a personalized, physician-reviewed protocol, backed by an Independent Medical Commission, free 1–2 day shipping, and a 90-day money-back guarantee.
Visit Enhanced.com →
He & She MD
The only major NAD+ provider that lets you pick your format, injection, cream, or nasal spray, without paying a cent more for the privilege.
Visit He & She MD →| Feature | Enhanced.com | He & She MD |
|---|---|---|
| Editorial score | 9.70 / 10 | 9.28 / 10 |
| Starting price | $139/mo (was $232, save 40%) | $149/mo (12-month supply) |
| Renewal / ongoing | $129–$149/mo by plan length | Flat $149/mo across every format |
| Delivery formats | Injection | Injection, topical cream & nasal spray |
| Dose strengths | Personalized clinician protocol (1–6 month supply) | Supplied as a 12-month course |
| Shipping | Free 1–2 day | Free expedited |
| Membership / fees | None | None: no membership cost |
| Guarantee | 90-day money-back guarantee | - |
| Best for | Adults already training and eating clean who want a personalized, clinician-supervised NAD+ protocol to make that effort translate into results again | People who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost |
Where Enhanced.com stands out
- + Lower entry price, $139/mo (was $232, save 40%)
- + Backed by a 90-day money-back guarantee
- + Higher editorial score (9.70 vs 9.28)
Where He & She MD stands out
- + More delivery formats, injection, topical cream & nasal spray
Pros & cons, side by side
Enhanced.com
Pros
- + Special offer: $232 down to $139/mo (save 40%), as low as $129/mo on the longest plan
- + 90-day money-back guarantee, no questions asked
- + Every prescription follows a remote clinician review of your goals and history
- + Overseen by an Independent Medical Commission of board-certified physicians
- + Plans scale from a 1-month to a 6-month supply, with the monthly rate falling as the term grows
- + Free shipping: arrives in 1–2 days
- + Ongoing clinical support for injection technique, shipping, and protocol adjustments
Cons
- − Compounded NAD+: not an FDA-approved finished drug product
- − Requires a clinician consultation before your protocol is issued
- − The lowest per-month rate requires a longer supply commitment
He & She MD
Pros
- + Three delivery formats: subcutaneous injection, topical cream, and nasal spray
- + Two needle-free options (cream and nasal spray), rare in this market
- + One flat $149/mo price across every format, locked on a 12-month supply
- + No membership fee, no hidden costs, and HSA/FSA cards accepted
- + 5-minute intake quiz reviewed by a licensed U.S. physician or DO
- + Unlimited provider messaging for as long as you are on the program
Cons
- − Compounded NAD+: not an FDA-approved finished drug product
- − The $149/mo rate is locked on a 12-month supply ($1,788/yr)
The verdict: Enhanced.com vs He & She MD
In our editorial ranking, Enhanced.com places higher (#7 vs #12), making it the default pick for most readers, it's best for adults already training and eating clean who want a personalized, clinician-supervised NAD+ protocol to make that effort translate into results again. That said, He & She MD is the stronger choice for people who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change, always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.
Independent provider research and pricing analysis
Non-clinical editorial team, see our disclosure
This page is independent editorial research, not medical advice, and has not been reviewed by a licensed clinician. NAD+ requires evaluation by a licensed healthcare professional, and a prescription is not guaranteed. Discuss your health history, medications and treatment goals with a qualified clinician before starting any treatment.
Medical Disclaimer
The information on BestNADTreatments.com is provided for educational and comparison purposes only. It is not medical advice and does not replace consultation with a qualified healthcare professional. NAD+ treatment requires evaluation by a licensed clinician, and a prescription is not guaranteed. Compounded medications are not FDA-approved, and treatment availability varies by state and provider.
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