DirectMeds vs Enhanced.com: NAD+ Therapy Compared
DirectMeds starts at $99 first month (500mg) and offers injection, while Enhanced.com starts at $139/mo (was $232 — save 40%) with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared
DirectMeds
DirectMeds delivers physician-prescribed NAD+ injections straight to your door, combining transparent all-inclusive pricing, fast US pharmacy fulfillment, and ongoing nursing support.
Visit DirectMeds →
Enhanced.com
Enhanced delivers NAD+Rx restored to clinical levels through a personalized, physician-reviewed protocol, backed by an Independent Medical Commission, free 1–2 day shipping, and a 90-day money-back guarantee.
Visit Enhanced.com →| Feature | DirectMeds | Enhanced.com |
|---|---|---|
| Editorial score | 9.78 / 10 | 9.70 / 10 |
| Starting price | $99 first month (500mg) | $139/mo (was $232 — save 40%) |
| Renewal / ongoing | $199 (500mg) / $249 (1000mg) | $129–$149/mo by plan length |
| Delivery formats | Injection | Injection |
| Dose strengths | 500mg & 1000mg | Personalized clinician protocol (1–6 month supply) |
| Shipping | Free 1–2 day | Free 1–2 day |
| Membership / fees | None — no subscription | None |
| Guarantee | Satisfaction guarantee | 90-day money-back guarantee |
| Best for | People who want prescription-grade, physician-reviewed NAD+ with all-inclusive pricing, no insurance, and 1–2 day delivery | Adults already training and eating clean who want a personalized, clinician-supervised NAD+ protocol to make that effort translate into results again |
Where DirectMeds stands out
- + Lower entry price — $99 first month (500mg)
- + Higher editorial score (9.78 vs 9.70)
Where Enhanced.com stands out
Enhanced.com is closely matched with DirectMeds on the headline metrics — the deciding factors come down to delivery format and the specifics below.
Pros & cons, side by side
DirectMeds
Pros
- + $100 off first month on the 500mg plan — $99 to start, then $199/mo
- + One transparent monthly price covering medication, consultation, and shipping
- + No insurance required and no hidden fees
- + Medication compounded by FDA-registered US pharmacies
- + Provider review typically within a day, then 1–2 day shipping with full tracking
- + LegitScript certified, with over 180,000 customers served and a 4.6-star Trustpilot rating
Cons
- − Injection-only — no nasal or oral option
- − The 500mg plan renews at $199/mo after the discounted first month
- − 1000mg plan renews at $249/mo
Enhanced.com
Pros
- + Special offer: $232 down to $139/mo (save 40%), as low as $129/mo on the longest plan
- + 90-day money-back guarantee — no questions asked
- + Every prescription follows a remote clinician review of your goals and history
- + Overseen by an Independent Medical Commission of board-certified physicians
- + Plans scale from a 1-month to a 6-month supply, with the monthly rate falling as the term grows
- + Free shipping — arrives in 1–2 days
- + Ongoing clinical support for injection technique, shipping, and protocol adjustments
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − Requires a clinician consultation before your protocol is issued
- − The lowest per-month rate requires a longer supply commitment
The verdict: DirectMeds vs Enhanced.com
In our editorial ranking, DirectMeds places higher (#6 vs #8), making it the default pick for most readers — it's best for people who want prescription-grade, physician-reviewed NAD+ with all-inclusive pricing, no insurance, and 1–2 day delivery. That said, Enhanced.com is the stronger choice for adults already training and eating clean who want a personalized, clinician-supervised NAD+ protocol to make that effort translate into results again. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.