DirectMeds vs ReadyRx: NAD+ Therapy Compared
DirectMeds starts at $99 first month (500mg) and offers injection, while ReadyRx starts at from $84 with injection + nasal spray. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared

DirectMeds
DirectMeds delivers physician-prescribed NAD+ injections straight to your door, combining transparent all-inclusive pricing, fast US pharmacy fulfillment, and ongoing nursing support.
Visit DirectMeds →
ReadyRx
A 100% online medical visit, 500mg to 1,000mg NAD+ injections from $84, and the same price at every dose with free 1–2 day shipping.
Visit ReadyRx →| Feature | DirectMeds | ReadyRx |
|---|---|---|
| Editorial score | 9.78 / 10 | 9.35 / 10 |
| Starting price | $99 first month (500mg) | From $84 |
| Renewal / ongoing | $199 (500mg) / $249 (1000mg) | Same price at every dose |
| Delivery formats | Injection | Injection + nasal spray |
| Dose strengths | 500mg & 1000mg | Injection 500/1000mg; nasal 4,500mg |
| Shipping | Free 1–2 day | Free — arrives in 1–2 days |
| Membership / fees | None — no subscription | None — cancel anytime |
| Guarantee | Satisfaction guarantee | Refundable if not eligible |
| Best for | People who want prescription-grade, physician-reviewed NAD+ with all-inclusive pricing, no insurance, and 1–2 day delivery | People who want a fully online NAD+ program with one price at every dose, no membership, and fast free shipping |
Where DirectMeds stands out
- + Higher editorial score (9.78 vs 9.35)
Where ReadyRx stands out
- + Lower entry price — From $84
- + More delivery formats — injection + nasal spray
Pros & cons, side by side
DirectMeds
Pros
- + $100 off first month on the 500mg plan — $99 to start, then $199/mo
- + One transparent monthly price covering medication, consultation, and shipping
- + No insurance required and no hidden fees
- + Medication compounded by FDA-registered US pharmacies
- + Provider review typically within a day, then 1–2 day shipping with full tracking
- + LegitScript certified, with over 180,000 customers served and a 4.6-star Trustpilot rating
Cons
- − Injection-only — no nasal or oral option
- − The 500mg plan renews at $199/mo after the discounted first month
- − 1000mg plan renews at $249/mo
ReadyRx
Pros
- + Same price at every dose, so titrating up does not raise the bill
- + Prescription and telemed visits included, and no insurance is required
- + Both injection (500–1,000mg) and a high-strength 4,500mg nasal spray
- + Free shipping that typically arrives in 1–2 days
- + No monthly membership and no hidden fees — cancel anytime
Cons
- − Live pricing is shown after you start the online intake
- − Not specialized exclusively in NAD+
The verdict: DirectMeds vs ReadyRx
In our editorial ranking, DirectMeds places higher (#6 vs #11), making it the default pick for most readers — it's best for people who want prescription-grade, physician-reviewed NAD+ with all-inclusive pricing, no insurance, and 1–2 day delivery. That said, ReadyRx is the stronger choice for people who want a fully online NAD+ program with one price at every dose, no membership, and fast free shipping. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.