DirectMeds vs Wellmedr: NAD+ Therapy Compared
DirectMeds starts at $99 first month (500mg) and offers injection, while Wellmedr starts at $99 with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks
DirectMeds
Save $100 first month — 500mg from $99, then $199. 250,000+ served. No subscription.
Visit DirectMeds →
Wellmedr
Starting at $99 — Physician-supervised NAD+ injections. No memberships. Free shipping.
Visit Wellmedr →| Feature | DirectMeds | Wellmedr |
|---|---|---|
| Editorial score | 9.64 / 10 | 9.78 / 10 |
| Starting price | $99 first month (500mg) | $99 |
| Renewal / ongoing | $199 (500mg) / $249 (1000mg) | Same price at every dose |
| Delivery formats | Injection | Injection |
| Dose strengths | 500mg & 1000mg | 500mg & 1000mg |
| Shipping | Free 1–2 day | Free 1–2 day |
| Membership / fees | None — no subscription | None |
| Guarantee | Satisfaction guarantee | — |
| Best for | People who want exact upfront pricing and no forced subscription, reordering on their own schedule | People seeking affordable physician-supervised NAD+ therapy without memberships or hidden fees |
Where DirectMeds stands out
- + Backed by a satisfaction guarantee
Where Wellmedr stands out
- + Higher editorial score (9.78 vs 9.64)
Pros & cons, side by side
DirectMeds
Pros
- + $100 off first month on the 500mg plan
- + Exact pricing shown upfront for both 500mg and 1000mg
- + No forced subscription — reorder manually when you want
- + 1:1 medical support with provider review within 24 hours
- + Free 1–2 day shipping included
Cons
- − Injection-only — no nasal or oral option
- − 1000mg plan renews at $249/mo
Wellmedr
Pros
- + Starts at $99 — one of the most accessible entry prices
- + Online consultation and prescription management included
- + No monthly membership or recurring commitments required
- + Free shipping on every order
- + 500mg and 1000mg dosage options available
- + Typically ships 1-2 days after approval
Cons
- − Newer platform with a smaller patient base
- − Limited public reviews compared to established providers
The verdict: DirectMeds vs Wellmedr
In our editorial ranking, DirectMeds places higher (#4 vs #6), making it the default pick for most readers — it's best for people who want exact upfront pricing and no forced subscription, reordering on their own schedule. That said, Wellmedr is the stronger choice for people seeking affordable physician-supervised NAD+ therapy without memberships or hidden fees. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.