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Wellmedr vs He & She MD: NAD+ Therapy Compared

  • Physician-prescribed only
  • 31 providers compared
← All NAD+ comparisons
Our #8 pick
Wellmedr logo

Wellmedr

9.55

Wellmedr offers licensed-provider NAD+ injections online, with flat transparent pricing, fast US pharmacy shipping, and no membership lock-in.

Visit Wellmedr →
VS
Our #12 pick
He & She MD logo

He & She MD

9.28

The only major NAD+ provider that lets you pick your format, injection, cream, or nasal spray, without paying a cent more for the privilege.

Visit He & She MD →
FeatureWellmedrHe & She MD
Editorial score9.55 / 109.28 / 10
Starting price$99$149/mo (12-month supply)
Renewal / ongoingSame price at every doseFlat $149/mo across every format
Delivery formatsInjectionInjection, topical cream & nasal spray
Dose strengths500mg & 1000mgSupplied as a 12-month course
ShippingFree 1–2 dayFree expedited
Membership / feesNoneNone: no membership cost
Guarantee--
Best forPeople seeking affordable licensed-provider NAD+ therapy with flat per-dose pricing and no membership lock-inPeople who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost

Where Wellmedr stands out

  • + Lower entry price, $99
  • + Higher editorial score (9.55 vs 9.28)

Where He & She MD stands out

  • + More delivery formats, injection, topical cream & nasal spray

Pros & cons, side by side

Wellmedr

Pros

  • + Starts at $99, one of the most accessible entry prices
  • + The same transparent price applies at every dose, with no hidden fees
  • + No mandatory membership: start, pause, or cancel at any time
  • + Free shipping, typically arriving within 1–2 days
  • + Prescriptions reviewed by US-based licensed providers and filled by FDA-registered compounding pharmacies
  • + 4.6-star Trustpilot rating, with verified reviews praising fast response times

Cons

  • − Newer platform with a smaller patient base
  • − Injection-only: no nasal or oral option

He & She MD

Pros

  • + Three delivery formats: subcutaneous injection, topical cream, and nasal spray
  • + Two needle-free options (cream and nasal spray), rare in this market
  • + One flat $149/mo price across every format, locked on a 12-month supply
  • + No membership fee, no hidden costs, and HSA/FSA cards accepted
  • + 5-minute intake quiz reviewed by a licensed U.S. physician or DO
  • + Unlimited provider messaging for as long as you are on the program

Cons

  • − Compounded NAD+: not an FDA-approved finished drug product
  • − The $149/mo rate is locked on a 12-month supply ($1,788/yr)

The verdict: Wellmedr vs He & She MD

In our editorial ranking, Wellmedr places higher (#8 vs #12), making it the default pick for most readers, it's best for people seeking affordable licensed-provider NAD+ therapy with flat per-dose pricing and no membership lock-in. That said, He & She MD is the stronger choice for people who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.

Pricing and product details were verified against each provider's official pages and may change, always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.

BestNADTreatments Editorial Team

Independent provider research and pricing analysis

Non-clinical editorial team, see our disclosure

Last Updated
October 1, 2026

This page is independent editorial research, not medical advice, and has not been reviewed by a licensed clinician. NAD+ requires evaluation by a licensed healthcare professional, and a prescription is not guaranteed. Discuss your health history, medications and treatment goals with a qualified clinician before starting any treatment.

Medical Disclaimer

The information on BestNADTreatments.com is provided for educational and comparison purposes only. It is not medical advice and does not replace consultation with a qualified healthcare professional. NAD+ treatment requires evaluation by a licensed clinician, and a prescription is not guaranteed. Compounded medications are not FDA-approved, and treatment availability varies by state and provider.

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Medical disclaimer: This page is for informational purposes only and is not medical advice. Always consult a licensed healthcare provider before starting any NAD+ therapy. We may earn a commission from partner links on this page - see our affiliate disclosure.