System NAD+ Review 2026: Nasal Spray From $69, Injection From $89
- Physician-prescribed only
- 30 providers compared
System is one of the cheapest ways to try NAD+ if you want to skip needles. Its nasal spray is $69 for the first month, and an injection is listed from $89. The catch is the second month: the spray renews at $119 and refills are automatic, so you will want to know that going in.
What Is System?
System sells treatments online, with NAD+ available as a nasal spray and an injection. There is no appointment to book. You pick the treatment, fill out a two-minute form, and a licensed provider reviews your information and contacts you by chat.
Its pricing is shown separately for each format, which makes it easy to compare them before you commit. Our NAD+ nasal spray page shows how its strength compares with other sprays.
The System NAD+ Nasal Spray
A monthly supply is 15ml at 300mg/ml. You use one spray per nostril, once or twice daily, as your clinician directs. It is needle-free and includes everything you need to take it.
System says the product is compounded by a certified US pharmacy and tested by a third party for potency, sterility, pH and endotoxins. That testing detail is worth more to us than most marketing claims.
On side effects, System mentions mild nasal irritation or a slight taste in the back of the throat, which it says are typically mild and short-lived. It adds that some people notice better energy and clarity in the first week while others see slower, subtler changes.
System NAD+ Pricing
The nasal spray is $69 for the first month and $119 a month after that. Injections are listed from $89 for the first month. Shipping is free and takes two days, and no insurance is required.
We could not confirm the injection's renewal price or vial strength from System's published pages, so check both during intake. See where it sits in our NAD+ treatment cost guide.
Check System Pricing →How Ordering Works
- 1
Select your treatment. Fill out a two-minute form. No appointment is needed.
- 2
Provider review. A licensed provider reviews your information and reaches out by chat.
- 3
Fulfilment. A certified US pharmacy compounds the order. Ongoing clinician support and free 2-day shipping are included.
Pros and Cons
Pros
- + Low $69 first month on the nasal spray
- + Injection and nasal spray both available
- + Third-party lab testing described on the product page
- + Free 2-day shipping and no insurance needed
- + Pause or cancel anytime
Cons
- − The spray rises to $119 after the first month
- − Refills are automatic, so you must pause or cancel to stop them
- − Injection strength and renewal price are not clearly published
- − Compounded NAD+ is not an FDA-approved finished product
System vs Alternatives
For a nasal spray plus an injection option at one provider, compare System with BettermeRx, which publishes a 900mg spray and flat pricing, or with DirectMeds, which is injection-only with everything bundled. Our provider selection guide covers what to check first.
Verdict
System is a low-cost way to try NAD+ in either format, and its testing disclosures are better than most. Treat $69 as a trial price, budget $119 for the spray afterward, and keep an eye on the automatic refills.
Get Started with System →System NAD+ FAQ
How much does System NAD+ cost?
The NAD+ nasal spray is $69 for the first month, then $119 a month. Our listing shows NAD+ injections from $89 for the first month. Insurance is not required.
What is in the System nasal spray?
A monthly supply is 15ml at 300mg/ml. The directions are one spray per nostril, once or twice daily, as your clinician directs.
Can I cancel System?
Refills are automatic, and System says you can pause or cancel anytime.
Is System tested?
System describes its NAD+ as third-party lab tested for potency, sterility, pH level and endotoxicity, and compounded by a certified US pharmacy.
Disclosure: This page contains affiliate links. BestNadTreatments.com may earn a commission at no extra cost to you if you purchase through them. Pricing, features and offers are subject to change; verify current details on the official System website. Rx required. A licensed healthcare professional will determine if treatment is appropriate for you. Compounded NAD+ is not an FDA-approved finished product, and NAD+ therapy is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary.
Independent provider research and pricing analysis
Non-clinical editorial team, see our disclosure
This page is independent editorial research, not medical advice, and has not been reviewed by a licensed clinician. NAD+ requires evaluation by a licensed healthcare professional, and a prescription is not guaranteed. Discuss your health history, medications and treatment goals with a qualified clinician before starting any treatment.
Medical Disclaimer
The information on BestNADTreatments.com is provided for educational and comparison purposes only. It is not medical advice and does not replace consultation with a qualified healthcare professional. NAD+ treatment requires evaluation by a licensed clinician, and a prescription is not guaranteed. Compounded medications are not FDA-approved, and treatment availability varies by state and provider.
Not Sure Where to Start?
Compare every NAD+ provider side by side on price, format, shipping and plan terms.
Compare Providers