Eden vs RXSpan: NAD+ Therapy Compared
Eden starts at $119 first month (~$15/shot) and offers injection (+ separate nasal spray), while RXSpan starts at ~$249 (recurring) with not disclosed. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks
Eden
NAD+ from $119 first month (~$15/shot). FSA/HSA eligible. Klarna & Afterpay available.
Visit Eden →RXSpan
NAD+ treatment starting at approximately $249. Online medical consultation included; recurring billing shown before checkout.
Visit RXSpan →| Feature | Eden | RXSpan |
|---|---|---|
| Editorial score | 8.27 / 10 | 8.40 / 10 |
| Starting price | $119 first month (~$15/shot) | ~$249 (recurring) |
| Renewal / ongoing | Medication + $99/mo membership | Recurring; shown before checkout |
| Delivery formats | Injection (+ separate nasal spray) | Not disclosed |
| Dose strengths | 500–1000mg at 200mg/mL | Not disclosed |
| Shipping | Free 2-day + home kit | Not stated |
| Membership / fees | $39 then $99/mo (required) | None |
| Guarantee | — | — |
| Best for | People who want flexible financing and FSA/HSA payment for physician-supervised NAD+ | People who want a physician-consulted NAD+ plan with clear recurring billing before checkout |
Where Eden stands out
- + Lower entry price — $119 first month (~$15/shot)
- + More delivery formats — injection (+ separate nasal spray)
Where RXSpan stands out
- + No required membership fee
- + Higher editorial score (8.40 vs 8.27)
Pros & cons, side by side
Eden
Pros
- + Low ~$15-per-shot framing with free 2-day shipping and home kit
- + FSA/HSA eligible
- + Pay over time with Klarna or Afterpay
- + 500–1000mg injections plus a separate nasal spray option
Cons
- − Requires an Eden membership ($39 first month, then $99/mo) on top of medication
- − Compounded NAD+ — not an FDA-approved finished product
RXSpan
Pros
- + Online medical consultation included
- + Recurring billing shown before checkout
- + Fully online process
Cons
- − Higher starting price than many competitors
- − Compounded NAD+ — not an FDA-approved finished product
The verdict: Eden vs RXSpan
In our editorial ranking, Eden places higher (#16 vs #21), making it the default pick for most readers — it's best for people who want flexible financing and FSA/HSA payment for physician-supervised NAD+. That said, RXSpan is the stronger choice for people who want a physician-consulted NAD+ plan with clear recurring billing before checkout. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.