DirectMeds vs Eden: NAD+ Therapy Compared
DirectMeds starts at $99 first month (500mg) and offers injection, while Eden starts at $119 first month (~$15/shot) with injection (+ separate nasal spray). Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared

DirectMeds
DirectMeds delivers physician-prescribed NAD+ injections straight to your door, combining transparent all-inclusive pricing, fast US pharmacy fulfillment, and ongoing nursing support.
Visit DirectMeds →Eden
NAD+ from $119 first month (~$15/shot). FSA/HSA eligible. Klarna & Afterpay available.
Visit Eden →| Feature | DirectMeds | Eden |
|---|---|---|
| Editorial score | 9.78 / 10 | 8.70 / 10 |
| Starting price | $99 first month (500mg) | $119 first month (~$15/shot) |
| Renewal / ongoing | $199 (500mg) / $249 (1000mg) | Medication + $99/mo membership |
| Delivery formats | Injection | Injection (+ separate nasal spray) |
| Dose strengths | 500mg & 1000mg | 500–1000mg at 200mg/mL |
| Shipping | Free 1–2 day | Free 2-day + home kit |
| Membership / fees | None — no subscription | $39 then $99/mo (required) |
| Guarantee | Satisfaction guarantee | — |
| Best for | People who want prescription-grade, physician-reviewed NAD+ with all-inclusive pricing, no insurance, and 1–2 day delivery | People who want flexible financing and FSA/HSA payment for physician-supervised NAD+ |
Where DirectMeds stands out
- + Lower entry price — $99 first month (500mg)
- + No required membership fee
- + Backed by a satisfaction guarantee
- + Higher editorial score (9.78 vs 8.70)
Where Eden stands out
- + More delivery formats — injection (+ separate nasal spray)
Pros & cons, side by side
DirectMeds
Pros
- + $100 off first month on the 500mg plan — $99 to start, then $199/mo
- + One transparent monthly price covering medication, consultation, and shipping
- + No insurance required and no hidden fees
- + Medication compounded by FDA-registered US pharmacies
- + Provider review typically within a day, then 1–2 day shipping with full tracking
- + LegitScript certified, with over 180,000 customers served and a 4.6-star Trustpilot rating
Cons
- − Injection-only — no nasal or oral option
- − The 500mg plan renews at $199/mo after the discounted first month
- − 1000mg plan renews at $249/mo
Eden
Pros
- + Low ~$15-per-shot framing with free 2-day shipping and home kit
- + FSA/HSA eligible
- + Pay over time with Klarna or Afterpay
- + 500–1000mg injections plus a separate nasal spray option
Cons
- − Requires an Eden membership ($39 first month, then $99/mo) on top of medication
- − Compounded NAD+ — not an FDA-approved finished product
The verdict: DirectMeds vs Eden
In our editorial ranking, DirectMeds places higher (#6 vs #18), making it the default pick for most readers — it's best for people who want prescription-grade, physician-reviewed NAD+ with all-inclusive pricing, no insurance, and 1–2 day delivery. That said, Eden is the stronger choice for people who want flexible financing and FSA/HSA payment for physician-supervised NAD+. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.