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BestNADTreatments
Updated on

Enhanced.com vs RXSpan: NAD+ Therapy Compared

Enhanced.com starts at $139/mo (was $232) and offers injection, while RXSpan starts at ~$249 (recurring) with not disclosed. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.

  • Physician-Prescribed Only
  • 22 Providers Compared
  • Results in 2–4 Weeks
← All NAD+ comparisons
Our #2 pick
Enhanced.com logo

Enhanced.com

9.90

NAD+Rx from $139/mo (was $232) — personalized, clinician-supervised NAD+ injections backed by a 90-day money-back guarantee, no questions asked. Free 1–2 day shipping.

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VS
Our #21 pick
RXSpan logo

RXSpan

8.40

NAD+ treatment starting at approximately $249. Online medical consultation included; recurring billing shown before checkout.

Visit RXSpan
FeatureEnhanced.comRXSpan
Editorial score9.90 / 108.40 / 10
Starting price$139/mo (was $232)~$249 (recurring)
Renewal / ongoing$129–$149/mo by plan lengthRecurring; shown before checkout
Delivery formatsInjectionNot disclosed
Dose strengthsPersonalized clinician protocolNot disclosed
ShippingFree 1–2 dayNot stated
Membership / feesNoneNone
Guarantee90-day money-back guarantee
Best forAdults who want a personalized, clinician-supervised NAD+ protocol backed by a 90-day money-back guaranteePeople who want a physician-consulted NAD+ plan with clear recurring billing before checkout

Where Enhanced.com stands out

  • + Lower entry price — $139/mo (was $232)
  • + Backed by a 90-day money-back guarantee
  • + Higher editorial score (9.90 vs 8.40)

Where RXSpan stands out

RXSpan is closely matched with Enhanced.com on the headline metrics — the deciding factors come down to delivery format and the specifics below.

Pros & cons, side by side

Enhanced.com

Pros

  • + Special offer: $139/mo (save 37%), as low as $129/mo on the 6-month plan
  • + 90-day money-back guarantee — no questions asked
  • + Personalized treatment plans from certified medical professionals
  • + Trusted by 20,000+ happy customers
  • + Free shipping — arrives in 1–2 days
  • + Prescribed and monitored by board-certified providers

Cons

  • Compounded NAD+ — not an FDA-approved finished drug product
  • Requires a clinician consultation before your protocol is issued

RXSpan

Pros

  • + Online medical consultation included
  • + Recurring billing shown before checkout
  • + Fully online process

Cons

  • Higher starting price than many competitors
  • Compounded NAD+ — not an FDA-approved finished product

The verdict: Enhanced.com vs RXSpan

In our editorial ranking, Enhanced.com places higher (#2 vs #21), making it the default pick for most readers — it's best for adults who want a personalized, clinician-supervised NAD+ protocol backed by a 90-day money-back guarantee. That said, RXSpan is the stronger choice for people who want a physician-consulted NAD+ plan with clear recurring billing before checkout. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.

Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.

Medical disclaimer: This page is for informational purposes only and is not medical advice. Always consult a licensed healthcare provider before starting any NAD+ therapy. We may earn a commission from partner links on this page — see our affiliate disclosure.