Enhanced.com vs RXSpan: NAD+ Therapy Compared
Enhanced.com starts at $139/mo (was $232 — save 40%) and offers injection, while RXSpan starts at ~$249 (recurring) with not disclosed. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared
Enhanced.com
Enhanced delivers NAD+Rx restored to clinical levels through a personalized, physician-reviewed protocol, backed by an Independent Medical Commission, free 1–2 day shipping, and a 90-day money-back guarantee.
Visit Enhanced.com →
RXSpan
NAD+ treatment starting at approximately $249. Online medical consultation included; recurring billing shown before checkout.
Visit RXSpan →| Feature | Enhanced.com | RXSpan |
|---|---|---|
| Editorial score | 9.70 / 10 | 7.90 / 10 |
| Starting price | $139/mo (was $232 — save 40%) | ~$249 (recurring) |
| Renewal / ongoing | $129–$149/mo by plan length | Recurring; shown before checkout |
| Delivery formats | Injection | Not disclosed |
| Dose strengths | Personalized clinician protocol (1–6 month supply) | Not disclosed |
| Shipping | Free 1–2 day | Not stated |
| Membership / fees | None | None |
| Guarantee | 90-day money-back guarantee | — |
| Best for | Adults already training and eating clean who want a personalized, clinician-supervised NAD+ protocol to make that effort translate into results again | People who want a physician-consulted NAD+ plan with clear recurring billing before checkout |
Where Enhanced.com stands out
- + Lower entry price — $139/mo (was $232 — save 40%)
- + Backed by a 90-day money-back guarantee
- + Higher editorial score (9.70 vs 7.90)
Where RXSpan stands out
RXSpan is closely matched with Enhanced.com on the headline metrics — the deciding factors come down to delivery format and the specifics below.
Pros & cons, side by side
Enhanced.com
Pros
- + Special offer: $232 down to $139/mo (save 40%), as low as $129/mo on the longest plan
- + 90-day money-back guarantee — no questions asked
- + Every prescription follows a remote clinician review of your goals and history
- + Overseen by an Independent Medical Commission of board-certified physicians
- + Plans scale from a 1-month to a 6-month supply, with the monthly rate falling as the term grows
- + Free shipping — arrives in 1–2 days
- + Ongoing clinical support for injection technique, shipping, and protocol adjustments
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − Requires a clinician consultation before your protocol is issued
- − The lowest per-month rate requires a longer supply commitment
RXSpan
Pros
- + Online medical consultation included
- + Recurring billing shown before checkout
- + Fully online process
Cons
- − Higher starting price than many competitors
- − Compounded NAD+ — not an FDA-approved finished product
The verdict: Enhanced.com vs RXSpan
In our editorial ranking, Enhanced.com places higher (#8 vs #26), making it the default pick for most readers — it's best for adults already training and eating clean who want a personalized, clinician-supervised NAD+ protocol to make that effort translate into results again. That said, RXSpan is the stronger choice for people who want a physician-consulted NAD+ plan with clear recurring billing before checkout. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.