He & She MD vs Enhanced.com: NAD+ Therapy Compared
He & She MD starts at $149/mo (12-month supply) and offers injection, topical cream & nasal spray, while Enhanced.com starts at $139/mo (was $232) with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks

He & She MD
Our #1 NAD+ pick — three formats (injection, cream, and nasal spray) at one flat $149/mo. No membership, no hidden fees, free shipping.
Visit He & She MD →
Enhanced.com
NAD+Rx from $139/mo (was $232) — personalized, clinician-supervised NAD+ injections backed by a 90-day money-back guarantee, no questions asked. Free 1–2 day shipping.
Visit Enhanced.com →| Feature | He & She MD | Enhanced.com |
|---|---|---|
| Editorial score | 9.90 / 10 | 9.90 / 10 |
| Starting price | $149/mo (12-month supply) | $139/mo (was $232) |
| Renewal / ongoing | Flat $149/mo across every format | $129–$149/mo by plan length |
| Delivery formats | Injection, topical cream & nasal spray | Injection |
| Dose strengths | Supplied as a 12-month course | Personalized clinician protocol |
| Shipping | Free expedited | Free 1–2 day |
| Membership / fees | None — no membership cost | None |
| Guarantee | — | 90-day money-back guarantee |
| Best for | People who want a choice of injection, cream, or nasal spray at one flat, transparent price with included ongoing care | Adults who want a personalized, clinician-supervised NAD+ protocol backed by a 90-day money-back guarantee |
Where He & She MD stands out
- + More delivery formats — injection, topical cream & nasal spray
Where Enhanced.com stands out
- + Lower entry price — $139/mo (was $232)
- + Backed by a 90-day money-back guarantee
Pros & cons, side by side
He & She MD
Pros
- + Three delivery formats — injection, topical cream, and nasal spray
- + Two needle-free options (cream and nasal spray), rare in this market
- + One flat $149/mo price across every format
- + No membership cost and no hidden fees
- + Board-certified providers and FDA-regulated dispensing pharmacies
- + Unlimited provider messaging for ongoing care
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − The $149/mo rate is tied to a 12-month supply commitment
Enhanced.com
Pros
- + Special offer: $139/mo (save 37%), as low as $129/mo on the 6-month plan
- + 90-day money-back guarantee — no questions asked
- + Personalized treatment plans from certified medical professionals
- + Trusted by 20,000+ happy customers
- + Free shipping — arrives in 1–2 days
- + Prescribed and monitored by board-certified providers
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − Requires a clinician consultation before your protocol is issued
The verdict: He & She MD vs Enhanced.com
In our editorial ranking, He & She MD places higher (#1 vs #2), making it the default pick for most readers — it's best for people who want a choice of injection, cream, or nasal spray at one flat, transparent price with included ongoing care. That said, Enhanced.com is the stronger choice for adults who want a personalized, clinician-supervised NAD+ protocol backed by a 90-day money-back guarantee. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.