He & She MD vs Enhanced.com: NAD+ Therapy Compared
He & She MD starts at $149/mo (12-month supply) and offers injection, topical cream & nasal spray, while Enhanced.com starts at $139/mo (was $232 — save 40%) with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared
He & She MD
The only major NAD+ provider that lets you pick your format — injection, cream, or nasal spray — without paying a cent more for the privilege.
Visit He & She MD →
Enhanced.com
Enhanced delivers NAD+Rx restored to clinical levels through a personalized, physician-reviewed protocol, backed by an Independent Medical Commission, free 1–2 day shipping, and a 90-day money-back guarantee.
Visit Enhanced.com →| Feature | He & She MD | Enhanced.com |
|---|---|---|
| Editorial score | 9.92 / 10 | 9.70 / 10 |
| Starting price | $149/mo (12-month supply) | $139/mo (was $232 — save 40%) |
| Renewal / ongoing | Flat $149/mo across every format | $129–$149/mo by plan length |
| Delivery formats | Injection, topical cream & nasal spray | Injection |
| Dose strengths | Supplied as a 12-month course | Personalized clinician protocol (1–6 month supply) |
| Shipping | Free expedited | Free 1–2 day |
| Membership / fees | None — no membership cost | None |
| Guarantee | — | 90-day money-back guarantee |
| Best for | People who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost | Adults already training and eating clean who want a personalized, clinician-supervised NAD+ protocol to make that effort translate into results again |
Where He & She MD stands out
- + More delivery formats — injection, topical cream & nasal spray
- + Higher editorial score (9.92 vs 9.70)
Where Enhanced.com stands out
- + Lower entry price — $139/mo (was $232 — save 40%)
- + Backed by a 90-day money-back guarantee
Pros & cons, side by side
He & She MD
Pros
- + Three delivery formats — subcutaneous injection, topical cream, and nasal spray
- + Two needle-free options (cream and nasal spray), rare in this market
- + One flat $149/mo price across every format, locked on a 12-month supply
- + No membership fee, no hidden costs, and HSA/FSA cards accepted
- + 5-minute intake quiz reviewed by a licensed U.S. physician or DO
- + Unlimited provider messaging for as long as you are on the program
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − The $149/mo rate is locked on a 12-month supply ($1,788/yr)
Enhanced.com
Pros
- + Special offer: $232 down to $139/mo (save 40%), as low as $129/mo on the longest plan
- + 90-day money-back guarantee — no questions asked
- + Every prescription follows a remote clinician review of your goals and history
- + Overseen by an Independent Medical Commission of board-certified physicians
- + Plans scale from a 1-month to a 6-month supply, with the monthly rate falling as the term grows
- + Free shipping — arrives in 1–2 days
- + Ongoing clinical support for injection technique, shipping, and protocol adjustments
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − Requires a clinician consultation before your protocol is issued
- − The lowest per-month rate requires a longer supply commitment
The verdict: He & She MD vs Enhanced.com
In our editorial ranking, He & She MD places higher (#1 vs #8), making it the default pick for most readers — it's best for people who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost. That said, Enhanced.com is the stronger choice for adults already training and eating clean who want a personalized, clinician-supervised NAD+ protocol to make that effort translate into results again. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.