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BestNADTreatments
Updated on

He & She MD vs Enhanced.com: NAD+ Therapy Compared

He & She MD starts at $149/mo (12-month supply) and offers injection, topical cream & nasal spray, while Enhanced.com starts at $139/mo (was $232) with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.

  • Physician-Prescribed Only
  • 22 Providers Compared
  • Results in 2–4 Weeks
← All NAD+ comparisons
Our #1 pick
He & She MD logo

He & She MD

9.90

Our #1 NAD+ pick — three formats (injection, cream, and nasal spray) at one flat $149/mo. No membership, no hidden fees, free shipping.

Visit He & She MD
VS
Our #2 pick
Enhanced.com logo

Enhanced.com

9.90

NAD+Rx from $139/mo (was $232) — personalized, clinician-supervised NAD+ injections backed by a 90-day money-back guarantee, no questions asked. Free 1–2 day shipping.

Visit Enhanced.com
FeatureHe & She MDEnhanced.com
Editorial score9.90 / 109.90 / 10
Starting price$149/mo (12-month supply)$139/mo (was $232)
Renewal / ongoingFlat $149/mo across every format$129–$149/mo by plan length
Delivery formatsInjection, topical cream & nasal sprayInjection
Dose strengthsSupplied as a 12-month coursePersonalized clinician protocol
ShippingFree expeditedFree 1–2 day
Membership / feesNone — no membership costNone
Guarantee90-day money-back guarantee
Best forPeople who want a choice of injection, cream, or nasal spray at one flat, transparent price with included ongoing careAdults who want a personalized, clinician-supervised NAD+ protocol backed by a 90-day money-back guarantee

Where He & She MD stands out

  • + More delivery formats — injection, topical cream & nasal spray

Where Enhanced.com stands out

  • + Lower entry price — $139/mo (was $232)
  • + Backed by a 90-day money-back guarantee

Pros & cons, side by side

He & She MD

Pros

  • + Three delivery formats — injection, topical cream, and nasal spray
  • + Two needle-free options (cream and nasal spray), rare in this market
  • + One flat $149/mo price across every format
  • + No membership cost and no hidden fees
  • + Board-certified providers and FDA-regulated dispensing pharmacies
  • + Unlimited provider messaging for ongoing care

Cons

  • Compounded NAD+ — not an FDA-approved finished drug product
  • The $149/mo rate is tied to a 12-month supply commitment

Enhanced.com

Pros

  • + Special offer: $139/mo (save 37%), as low as $129/mo on the 6-month plan
  • + 90-day money-back guarantee — no questions asked
  • + Personalized treatment plans from certified medical professionals
  • + Trusted by 20,000+ happy customers
  • + Free shipping — arrives in 1–2 days
  • + Prescribed and monitored by board-certified providers

Cons

  • Compounded NAD+ — not an FDA-approved finished drug product
  • Requires a clinician consultation before your protocol is issued

The verdict: He & She MD vs Enhanced.com

In our editorial ranking, He & She MD places higher (#1 vs #2), making it the default pick for most readers — it's best for people who want a choice of injection, cream, or nasal spray at one flat, transparent price with included ongoing care. That said, Enhanced.com is the stronger choice for adults who want a personalized, clinician-supervised NAD+ protocol backed by a 90-day money-back guarantee. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.

Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.

Medical disclaimer: This page is for informational purposes only and is not medical advice. Always consult a licensed healthcare provider before starting any NAD+ therapy. We may earn a commission from partner links on this page — see our affiliate disclosure.