He & She MD vs Wellmedr: NAD+ Therapy Compared
He & She MD starts at $149/mo (12-month supply) and offers injection, topical cream & nasal spray, while Wellmedr starts at $99 with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared
He & She MD
The only major NAD+ provider that lets you pick your format — injection, cream, or nasal spray — without paying a cent more for the privilege.
Visit He & She MD →
Wellmedr
Wellmedr offers licensed-provider NAD+ injections online, with flat transparent pricing, fast US pharmacy shipping, and no membership lock-in.
Visit Wellmedr →| Feature | He & She MD | Wellmedr |
|---|---|---|
| Editorial score | 9.92 / 10 | 9.55 / 10 |
| Starting price | $149/mo (12-month supply) | $99 |
| Renewal / ongoing | Flat $149/mo across every format | Same price at every dose |
| Delivery formats | Injection, topical cream & nasal spray | Injection |
| Dose strengths | Supplied as a 12-month course | 500mg & 1000mg |
| Shipping | Free expedited | Free 1–2 day |
| Membership / fees | None — no membership cost | None |
| Guarantee | — | — |
| Best for | People who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost | People seeking affordable licensed-provider NAD+ therapy with flat per-dose pricing and no membership lock-in |
Where He & She MD stands out
- + More delivery formats — injection, topical cream & nasal spray
- + Higher editorial score (9.92 vs 9.55)
Where Wellmedr stands out
- + Lower entry price — $99
Pros & cons, side by side
He & She MD
Pros
- + Three delivery formats — subcutaneous injection, topical cream, and nasal spray
- + Two needle-free options (cream and nasal spray), rare in this market
- + One flat $149/mo price across every format, locked on a 12-month supply
- + No membership fee, no hidden costs, and HSA/FSA cards accepted
- + 5-minute intake quiz reviewed by a licensed U.S. physician or DO
- + Unlimited provider messaging for as long as you are on the program
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − The $149/mo rate is locked on a 12-month supply ($1,788/yr)
Wellmedr
Pros
- + Starts at $99 — one of the most accessible entry prices
- + The same transparent price applies at every dose, with no hidden fees
- + No mandatory membership — start, pause, or cancel at any time
- + Free shipping, typically arriving within 1–2 days
- + Prescriptions reviewed by US-based licensed providers and filled by FDA-registered compounding pharmacies
- + 4.6-star Trustpilot rating, with verified reviews praising fast response times
Cons
- − Newer platform with a smaller patient base
- − Injection-only — no nasal or oral option
The verdict: He & She MD vs Wellmedr
In our editorial ranking, He & She MD places higher (#1 vs #9), making it the default pick for most readers — it's best for people who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost. That said, Wellmedr is the stronger choice for people seeking affordable licensed-provider NAD+ therapy with flat per-dose pricing and no membership lock-in. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.