He & She MD vs ReadyRx: NAD+ Therapy Compared
He & She MD starts at $149/mo (12-month supply) and offers injection, topical cream & nasal spray, while ReadyRx starts at from $84 with injection + nasal spray. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared

He & She MD
The only major NAD+ provider that lets you pick your format — injection, cream, or nasal spray — without paying a cent more for the privilege.
Visit He & She MD →
ReadyRx
A 100% online medical visit, 500mg to 1,000mg NAD+ injections from $84, and the same price at every dose with free 1–2 day shipping.
Visit ReadyRx →| Feature | He & She MD | ReadyRx |
|---|---|---|
| Editorial score | 9.92 / 10 | 9.35 / 10 |
| Starting price | $149/mo (12-month supply) | From $84 |
| Renewal / ongoing | Flat $149/mo across every format | Same price at every dose |
| Delivery formats | Injection, topical cream & nasal spray | Injection + nasal spray |
| Dose strengths | Supplied as a 12-month course | Injection 500/1000mg; nasal 4,500mg |
| Shipping | Free expedited | Free — arrives in 1–2 days |
| Membership / fees | None — no membership cost | None — cancel anytime |
| Guarantee | — | Refundable if not eligible |
| Best for | People who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost | People who want a fully online NAD+ program with one price at every dose, no membership, and fast free shipping |
Where He & She MD stands out
- + Higher editorial score (9.92 vs 9.35)
Where ReadyRx stands out
- + Lower entry price — From $84
- + Backed by a refundable if not eligible
Pros & cons, side by side
He & She MD
Pros
- + Three delivery formats — subcutaneous injection, topical cream, and nasal spray
- + Two needle-free options (cream and nasal spray), rare in this market
- + One flat $149/mo price across every format, locked on a 12-month supply
- + No membership fee, no hidden costs, and HSA/FSA cards accepted
- + 5-minute intake quiz reviewed by a licensed U.S. physician or DO
- + Unlimited provider messaging for as long as you are on the program
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − The $149/mo rate is locked on a 12-month supply ($1,788/yr)
ReadyRx
Pros
- + Same price at every dose, so titrating up does not raise the bill
- + Prescription and telemed visits included, and no insurance is required
- + Both injection (500–1,000mg) and a high-strength 4,500mg nasal spray
- + Free shipping that typically arrives in 1–2 days
- + No monthly membership and no hidden fees — cancel anytime
Cons
- − Live pricing is shown after you start the online intake
- − Not specialized exclusively in NAD+
The verdict: He & She MD vs ReadyRx
In our editorial ranking, He & She MD places higher (#1 vs #11), making it the default pick for most readers — it's best for people who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost. That said, ReadyRx is the stronger choice for people who want a fully online NAD+ program with one price at every dose, no membership, and fast free shipping. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.