He & She MD vs BettermeRx: NAD+ Therapy Compared
He & She MD starts at $149/mo (12-month supply) and offers injection, topical cream & nasal spray, while BettermeRx starts at shown after free evaluation with injection, nasal spray & liposomal oral. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks
He & She MD
Our #1 NAD+ pick — three formats (injection, cream, and nasal spray) at one flat $149/mo. No membership, no hidden fees, free shipping.
Visit He & She MD →
BettermeRx
Three NAD+ formats — injection, nasal spray, and liposomal. Flat pricing, no hidden fees.
Visit BettermeRx →| Feature | He & She MD | BettermeRx |
|---|---|---|
| Editorial score | 9.90 / 10 | 9.72 / 10 |
| Starting price | $149/mo (12-month supply) | Shown after free evaluation |
| Renewal / ongoing | Flat $149/mo across every format | Flat pricing, no increases |
| Delivery formats | Injection, topical cream & nasal spray | Injection, nasal spray & liposomal oral |
| Dose strengths | Supplied as a 12-month course | Injection 500/1000mg; nasal 900mg |
| Shipping | Free expedited | Free UPS/FedEx |
| Membership / fees | None — no membership cost | None |
| Guarantee | — | — |
| Best for | People who want a choice of injection, cream, or nasal spray at one flat, transparent price with included ongoing care | People who want to choose between injection, nasal spray, or liposomal NAD+ with flat, no-surprise pricing |
Where He & She MD stands out
- + Lower entry price — $149/mo (12-month supply)
- + Pricing shown upfront, before you start intake
- + Higher editorial score (9.90 vs 9.72)
Where BettermeRx stands out
- + More delivery formats — injection, nasal spray & liposomal oral
Pros & cons, side by side
He & She MD
Pros
- + Three delivery formats — injection, topical cream, and nasal spray
- + Two needle-free options (cream and nasal spray), rare in this market
- + One flat $149/mo price across every format
- + No membership cost and no hidden fees
- + Board-certified providers and FDA-regulated dispensing pharmacies
- + Unlimited provider messaging for ongoing care
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − The $149/mo rate is tied to a 12-month supply commitment
BettermeRx
Pros
- + Widest format choice: injection, nasal spray, and liposomal oral
- + Flat, all-inclusive pricing with no hidden fees
- + Free UPS/FedEx shipping on every order
- + U.S. board-certified physician evaluation included
Cons
- − Your exact price is shown after a free online evaluation
- − Compounded NAD+ — not an FDA-approved finished product
The verdict: He & She MD vs BettermeRx
In our editorial ranking, He & She MD places higher (#1 vs #8), making it the default pick for most readers — it's best for people who want a choice of injection, cream, or nasal spray at one flat, transparent price with included ongoing care. That said, BettermeRx is the stronger choice for people who want to choose between injection, nasal spray, or liposomal NAD+ with flat, no-surprise pricing. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.