Fridays vs RXSpan: NAD+ Therapy Compared
Fridays starts at $179/mo (billed quarterly) and offers injection, nasal spray & oral liposomal, while RXSpan starts at ~$249 (recurring) with not disclosed. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks
Fridays
NAD+ from $179/mo (billed quarterly). Injection, nasal spray, or oral liposomal.
Visit Fridays →RXSpan
NAD+ treatment starting at approximately $249. Online medical consultation included; recurring billing shown before checkout.
Visit RXSpan →| Feature | Fridays | RXSpan |
|---|---|---|
| Editorial score | 9.43 / 10 | 8.40 / 10 |
| Starting price | $179/mo (billed quarterly) | ~$249 (recurring) |
| Renewal / ongoing | Nasal & oral $229/mo | Recurring; shown before checkout |
| Delivery formats | Injection, nasal spray & oral liposomal | Not disclosed |
| Dose strengths | Oral 50/100/150mg daily; injection 3×/week | Not disclosed |
| Shipping | Medication included | Not stated |
| Membership / fees | None | None |
| Guarantee | — | — |
| Best for | People wanting personalized NAD+ with a choice of injection, nasal spray, or oral delivery | People who want a physician-consulted NAD+ plan with clear recurring billing before checkout |
Where Fridays stands out
- + Lower entry price — $179/mo (billed quarterly)
- + More delivery formats — injection, nasal spray & oral liposomal
- + Higher editorial score (9.43 vs 8.40)
Where RXSpan stands out
RXSpan is closely matched with Fridays on the headline metrics — the deciding factors come down to delivery format and the specifics below.
Pros & cons, side by side
Fridays
Pros
- + One of the few providers offering injection, nasal spray, AND oral liposomal NAD+
- + Personalized protocol for your goals
- + Established trusted brand
Cons
- − Billed quarterly rather than month-to-month
- − Not available in all states
RXSpan
Pros
- + Online medical consultation included
- + Recurring billing shown before checkout
- + Fully online process
Cons
- − Higher starting price than many competitors
- − Compounded NAD+ — not an FDA-approved finished product
The verdict: Fridays vs RXSpan
In our editorial ranking, Fridays places higher (#11 vs #21), making it the default pick for most readers — it's best for people wanting personalized NAD+ with a choice of injection, nasal spray, or oral delivery. That said, RXSpan is the stronger choice for people who want a physician-consulted NAD+ plan with clear recurring billing before checkout. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.