System vs Fridays: NAD+ Therapy Compared
System starts at injection $89 · nasal $69 (first month) and offers injection + nasal spray, while Fridays starts at $179/mo (billed quarterly) with injection, nasal spray & oral liposomal. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared
System
NAD+ injections from $89 and nasal treatment from $69 for the first month. Injection and nasal pricing shown separately.
Visit System →
Fridays
NAD+ from $179/mo (billed quarterly). Injection, nasal spray, or oral liposomal.
Visit Fridays →| Feature | System | Fridays |
|---|---|---|
| Editorial score | 9.82 / 10 | 9.15 / 10 |
| Starting price | Injection $89 · nasal $69 (first month) | $179/mo (billed quarterly) |
| Renewal / ongoing | Shown during intake | Nasal & oral $229/mo |
| Delivery formats | Injection + nasal spray | Injection, nasal spray & oral liposomal |
| Dose strengths | Not disclosed | Oral 50/100/150mg daily; injection 3×/week |
| Shipping | Not stated | Medication included |
| Membership / fees | None | None |
| Guarantee | — | — |
| Best for | People choosing between injectable and nasal NAD+ with separate, accessible first-month pricing | People wanting personalized NAD+ with a choice of injection, nasal spray, or oral delivery |
Where System stands out
- + Lower entry price — Injection $89 · nasal $69 (first month)
- + Higher editorial score (9.82 vs 9.15)
Where Fridays stands out
- + More delivery formats — injection, nasal spray & oral liposomal
Pros & cons, side by side
System
Pros
- + Both injection and nasal NAD+ options
- + Accessible first-month pricing
- + Fully online process
Cons
- − Compounded NAD+ — not an FDA-approved finished product
- − Ongoing pricing shown during intake
Fridays
Pros
- + One of the few providers offering injection, nasal spray, AND oral liposomal NAD+
- + Personalized protocol for your goals
- + Established trusted brand
Cons
- − Billed quarterly rather than month-to-month
- − Not available in all states
The verdict: System vs Fridays
In our editorial ranking, System places higher (#5 vs #13), making it the default pick for most readers — it's best for people choosing between injectable and nasal NAD+ with separate, accessible first-month pricing. That said, Fridays is the stronger choice for people wanting personalized NAD+ with a choice of injection, nasal spray, or oral delivery. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.