Fridays vs Tmates: NAD+ Therapy Compared
Fridays starts at $179/mo (billed quarterly) and offers injection, nasal spray & oral liposomal, while Tmates starts at $149/mo (as low as ~$88 on longer plans) with not disclosed. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks
Fridays
NAD+ from $179/mo (billed quarterly). Injection, nasal spray, or oral liposomal.
Visit Fridays →
Tmates
NAD+ treatment from $149 for one month, as low as approximately $88 monthly on longer plans.
Visit Tmates →| Feature | Fridays | Tmates |
|---|---|---|
| Editorial score | 9.43 / 10 | 8.60 / 10 |
| Starting price | $179/mo (billed quarterly) | $149/mo (as low as ~$88 on longer plans) |
| Renewal / ongoing | Nasal & oral $229/mo | From ~$88/mo on longer plans |
| Delivery formats | Injection, nasal spray & oral liposomal | Not disclosed |
| Dose strengths | Oral 50/100/150mg daily; injection 3×/week | Not disclosed |
| Shipping | Medication included | Not stated |
| Membership / fees | None | None |
| Guarantee | — | — |
| Best for | People wanting personalized NAD+ with a choice of injection, nasal spray, or oral delivery | People comfortable with a longer plan commitment to reach the lowest monthly NAD+ price |
Where Fridays stands out
- + More delivery formats — injection, nasal spray & oral liposomal
- + Higher editorial score (9.43 vs 8.60)
Where Tmates stands out
- + Lower entry price — $149/mo (as low as ~$88 on longer plans)
Pros & cons, side by side
Fridays
Pros
- + One of the few providers offering injection, nasal spray, AND oral liposomal NAD+
- + Personalized protocol for your goals
- + Established trusted brand
Cons
- − Billed quarterly rather than month-to-month
- − Not available in all states
Tmates
Pros
- + Lower monthly cost on longer plans
- + HSA/FSA eligible
- + Fully online intake
Cons
- − Lowest price requires a longer commitment
- − Compounded NAD+ — not an FDA-approved finished product
The verdict: Fridays vs Tmates
In our editorial ranking, Fridays places higher (#11 vs #19), making it the default pick for most readers — it's best for people wanting personalized NAD+ with a choice of injection, nasal spray, or oral delivery. That said, Tmates is the stronger choice for people comfortable with a longer plan commitment to reach the lowest monthly NAD+ price. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.