Shed vs System: NAD+ Therapy Compared
Shed starts at $144/mo nasal (20% off first month) and offers nasal spray, injection & oral tablets, while System starts at injection $89 · nasal $69 (first month) with injection + nasal spray. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks

Shed
Three NAD+ formats: nasal, injections, and oral. Coaching resources included.
Visit Shed →System
NAD+ injections from $89 and nasal treatment from $69 for the first month. Injection and nasal pricing shown separately.
Visit System →| Feature | Shed | System |
|---|---|---|
| Editorial score | 8.94 / 10 | 8.70 / 10 |
| Starting price | $144/mo nasal (20% off first month) | Injection $89 · nasal $69 (first month) |
| Renewal / ongoing | $144 nasal / $169 injection & oral | Shown during intake |
| Delivery formats | Nasal spray, injection & oral tablets | Injection + nasal spray |
| Dose strengths | Provider-determined | Not disclosed |
| Shipping | To your door | Not stated |
| Membership / fees | None — 1:1 coaching is an optional add-on | None |
| Guarantee | — | — |
| Best for | People who want format choice plus built-in wellness coaching resources | People choosing between injectable and nasal NAD+ with separate, accessible first-month pricing |
Where Shed stands out
- + More delivery formats — nasal spray, injection & oral tablets
- + Higher editorial score (8.94 vs 8.70)
Where System stands out
- + Lower entry price — Injection $89 · nasal $69 (first month)
Pros & cons, side by side
Shed
Pros
- + Three delivery formats: nasal spray, injection, and oral tablets
- + Health courses and community included
- + Strong 4.6-star Trustpilot rating
Cons
- − 1-on-1 coaching is a paid add-on
- − Cancellation requires completing at least two months
System
Pros
- + Both injection and nasal NAD+ options
- + Accessible first-month pricing
- + Fully online process
Cons
- − Compounded NAD+ — not an FDA-approved finished product
- − Ongoing pricing shown during intake
The verdict: Shed vs System
In our editorial ranking, Shed places higher (#13 vs #18), making it the default pick for most readers — it's best for people who want format choice plus built-in wellness coaching resources. That said, System is the stronger choice for people choosing between injectable and nasal NAD+ with separate, accessible first-month pricing. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.