System vs Shed: NAD+ Therapy Compared
System starts at injection $89 · nasal $69 (first month) and offers injection + nasal spray, while Shed starts at $144/mo nasal (20% off first month) with nasal spray, injection & oral tablets. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared
System
NAD+ injections from $89 and nasal treatment from $69 for the first month. Injection and nasal pricing shown separately.
Visit System →
Shed
Three NAD+ formats: nasal, injections, and oral. Coaching resources included.
Visit Shed →| Feature | System | Shed |
|---|---|---|
| Editorial score | 9.82 / 10 | 9.00 / 10 |
| Starting price | Injection $89 · nasal $69 (first month) | $144/mo nasal (20% off first month) |
| Renewal / ongoing | Shown during intake | $144 nasal / $169 injection & oral |
| Delivery formats | Injection + nasal spray | Nasal spray, injection & oral tablets |
| Dose strengths | Not disclosed | Provider-determined |
| Shipping | Not stated | To your door |
| Membership / fees | None | None — 1:1 coaching is an optional add-on |
| Guarantee | — | — |
| Best for | People choosing between injectable and nasal NAD+ with separate, accessible first-month pricing | People who want format choice plus built-in wellness coaching resources |
Where System stands out
- + Lower entry price — Injection $89 · nasal $69 (first month)
- + Higher editorial score (9.82 vs 9.00)
Where Shed stands out
- + More delivery formats — nasal spray, injection & oral tablets
Pros & cons, side by side
System
Pros
- + Both injection and nasal NAD+ options
- + Accessible first-month pricing
- + Fully online process
Cons
- − Compounded NAD+ — not an FDA-approved finished product
- − Ongoing pricing shown during intake
Shed
Pros
- + Three delivery formats: nasal spray, injection, and oral tablets
- + Health courses and community included
- + Strong 4.6-star Trustpilot rating
Cons
- − 1-on-1 coaching is a paid add-on
- − Cancellation requires completing at least two months
The verdict: System vs Shed
In our editorial ranking, System places higher (#5 vs #15), making it the default pick for most readers — it's best for people choosing between injectable and nasal NAD+ with separate, accessible first-month pricing. That said, Shed is the stronger choice for people who want format choice plus built-in wellness coaching resources. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.