Tmates vs RXSpan: NAD+ Therapy Compared
Tmates starts at $149/mo (as low as ~$88 on longer plans) and offers not disclosed, while RXSpan starts at ~$249 (recurring) with not disclosed. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks
Tmates
NAD+ treatment from $149 for one month, as low as approximately $88 monthly on longer plans.
Visit Tmates →RXSpan
NAD+ treatment starting at approximately $249. Online medical consultation included; recurring billing shown before checkout.
Visit RXSpan →| Feature | Tmates | RXSpan |
|---|---|---|
| Editorial score | 8.60 / 10 | 8.40 / 10 |
| Starting price | $149/mo (as low as ~$88 on longer plans) | ~$249 (recurring) |
| Renewal / ongoing | From ~$88/mo on longer plans | Recurring; shown before checkout |
| Delivery formats | Not disclosed | Not disclosed |
| Dose strengths | Not disclosed | Not disclosed |
| Shipping | Not stated | Not stated |
| Membership / fees | None | None |
| Guarantee | — | — |
| Best for | People comfortable with a longer plan commitment to reach the lowest monthly NAD+ price | People who want a physician-consulted NAD+ plan with clear recurring billing before checkout |
Where Tmates stands out
- + Lower entry price — $149/mo (as low as ~$88 on longer plans)
- + Higher editorial score (8.60 vs 8.40)
Where RXSpan stands out
RXSpan is closely matched with Tmates on the headline metrics — the deciding factors come down to delivery format and the specifics below.
Pros & cons, side by side
Tmates
Pros
- + Lower monthly cost on longer plans
- + HSA/FSA eligible
- + Fully online intake
Cons
- − Lowest price requires a longer commitment
- − Compounded NAD+ — not an FDA-approved finished product
RXSpan
Pros
- + Online medical consultation included
- + Recurring billing shown before checkout
- + Fully online process
Cons
- − Higher starting price than many competitors
- − Compounded NAD+ — not an FDA-approved finished product
The verdict: Tmates vs RXSpan
In our editorial ranking, Tmates places higher (#19 vs #21), making it the default pick for most readers — it's best for people comfortable with a longer plan commitment to reach the lowest monthly NAD+ price. That said, RXSpan is the stronger choice for people who want a physician-consulted NAD+ plan with clear recurring billing before checkout. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.