Shed vs Enhance MD: NAD+ Therapy Compared
Shed starts at $144/mo nasal (20% off first month) and offers nasal spray, injection & oral tablets, while Enhance MD starts at wafers $84/mo; injection $169/mo with injection + sublingual wafer. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks
Shed
Three NAD+ formats: nasal, injections, and oral. Coaching resources included.
Visit Shed →
Enhance MD
Injections or needle-free sublingual wafers. Physician oversight included.
Visit Enhance MD →| Feature | Shed | Enhance MD |
|---|---|---|
| Editorial score | 8.94 / 10 | 8.51 / 10 |
| Starting price | $144/mo nasal (20% off first month) | Wafers $84/mo; injection $169/mo |
| Renewal / ongoing | $144 nasal / $169 injection & oral | Wafers $84–$99; injection $169–$199 |
| Delivery formats | Nasal spray, injection & oral tablets | Injection + sublingual wafer |
| Dose strengths | Provider-determined | Per physician protocol |
| Shipping | To your door | Included |
| Membership / fees | None — 1:1 coaching is an optional add-on | None |
| Guarantee | — | Refund if ineligible |
| Best for | People who want format choice plus built-in wellness coaching resources | People weighing injectable NAD+ against a needle-free sublingual wafer with full price transparency |
Where Shed stands out
- + More delivery formats — nasal spray, injection & oral tablets
- + Higher editorial score (8.94 vs 8.51)
Where Enhance MD stands out
- + Lower entry price — Wafers $84/mo; injection $169/mo
- + Backed by a refund if ineligible
Pros & cons, side by side
Shed
Pros
- + Three delivery formats: nasal spray, injection, and oral tablets
- + Health courses and community included
- + Strong 4.6-star Trustpilot rating
Cons
- − 1-on-1 coaching is a paid add-on
- − Cancellation requires completing at least two months
Enhance MD
Pros
- + Needle-free sublingual wafer alternative to injections
- + Full published pricing matrix by commitment length
- + Provider check-ins and unlimited messaging included
- + Full refund if found ineligible
Cons
- − Lowest prices require a 12-month prepaid commitment
- − No nasal spray option
The verdict: Shed vs Enhance MD
In our editorial ranking, Shed places higher (#13 vs #15), making it the default pick for most readers — it's best for people who want format choice plus built-in wellness coaching resources. That said, Enhance MD is the stronger choice for people weighing injectable NAD+ against a needle-free sublingual wafer with full price transparency. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.