Shed vs RXSpan: NAD+ Therapy Compared
Shed starts at $144/mo nasal (20% off first month) and offers nasal spray, injection & oral tablets, while RXSpan starts at ~$249 (recurring) with not disclosed. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks
Shed
Three NAD+ formats: nasal, injections, and oral. Coaching resources included.
Visit Shed →RXSpan
NAD+ treatment starting at approximately $249. Online medical consultation included; recurring billing shown before checkout.
Visit RXSpan →| Feature | Shed | RXSpan |
|---|---|---|
| Editorial score | 8.94 / 10 | 8.40 / 10 |
| Starting price | $144/mo nasal (20% off first month) | ~$249 (recurring) |
| Renewal / ongoing | $144 nasal / $169 injection & oral | Recurring; shown before checkout |
| Delivery formats | Nasal spray, injection & oral tablets | Not disclosed |
| Dose strengths | Provider-determined | Not disclosed |
| Shipping | To your door | Not stated |
| Membership / fees | None — 1:1 coaching is an optional add-on | None |
| Guarantee | — | — |
| Best for | People who want format choice plus built-in wellness coaching resources | People who want a physician-consulted NAD+ plan with clear recurring billing before checkout |
Where Shed stands out
- + Lower entry price — $144/mo nasal (20% off first month)
- + More delivery formats — nasal spray, injection & oral tablets
- + Higher editorial score (8.94 vs 8.40)
Where RXSpan stands out
RXSpan is closely matched with Shed on the headline metrics — the deciding factors come down to delivery format and the specifics below.
Pros & cons, side by side
Shed
Pros
- + Three delivery formats: nasal spray, injection, and oral tablets
- + Health courses and community included
- + Strong 4.6-star Trustpilot rating
Cons
- − 1-on-1 coaching is a paid add-on
- − Cancellation requires completing at least two months
RXSpan
Pros
- + Online medical consultation included
- + Recurring billing shown before checkout
- + Fully online process
Cons
- − Higher starting price than many competitors
- − Compounded NAD+ — not an FDA-approved finished product
The verdict: Shed vs RXSpan
In our editorial ranking, Shed places higher (#13 vs #21), making it the default pick for most readers — it's best for people who want format choice plus built-in wellness coaching resources. That said, RXSpan is the stronger choice for people who want a physician-consulted NAD+ plan with clear recurring billing before checkout. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.