Shed vs Tmates: NAD+ Therapy Compared
Shed starts at $144/mo nasal (20% off first month) and offers nasal spray, injection & oral tablets, while Tmates starts at $149/mo (as low as ~$88 on longer plans) with not disclosed. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 22 Providers Compared
- Results in 2–4 Weeks
Shed
Three NAD+ formats: nasal, injections, and oral. Coaching resources included.
Visit Shed →
Tmates
NAD+ treatment from $149 for one month, as low as approximately $88 monthly on longer plans.
Visit Tmates →| Feature | Shed | Tmates |
|---|---|---|
| Editorial score | 8.94 / 10 | 8.60 / 10 |
| Starting price | $144/mo nasal (20% off first month) | $149/mo (as low as ~$88 on longer plans) |
| Renewal / ongoing | $144 nasal / $169 injection & oral | From ~$88/mo on longer plans |
| Delivery formats | Nasal spray, injection & oral tablets | Not disclosed |
| Dose strengths | Provider-determined | Not disclosed |
| Shipping | To your door | Not stated |
| Membership / fees | None — 1:1 coaching is an optional add-on | None |
| Guarantee | — | — |
| Best for | People who want format choice plus built-in wellness coaching resources | People comfortable with a longer plan commitment to reach the lowest monthly NAD+ price |
Where Shed stands out
- + Lower entry price — $144/mo nasal (20% off first month)
- + More delivery formats — nasal spray, injection & oral tablets
- + Higher editorial score (8.94 vs 8.60)
Where Tmates stands out
Tmates is closely matched with Shed on the headline metrics — the deciding factors come down to delivery format and the specifics below.
Pros & cons, side by side
Shed
Pros
- + Three delivery formats: nasal spray, injection, and oral tablets
- + Health courses and community included
- + Strong 4.6-star Trustpilot rating
Cons
- − 1-on-1 coaching is a paid add-on
- − Cancellation requires completing at least two months
Tmates
Pros
- + Lower monthly cost on longer plans
- + HSA/FSA eligible
- + Fully online intake
Cons
- − Lowest price requires a longer commitment
- − Compounded NAD+ — not an FDA-approved finished product
The verdict: Shed vs Tmates
In our editorial ranking, Shed places higher (#13 vs #19), making it the default pick for most readers — it's best for people who want format choice plus built-in wellness coaching resources. That said, Tmates is the stronger choice for people comfortable with a longer plan commitment to reach the lowest monthly NAD+ price. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.