He & She MD vs RNK Health: NAD+ Therapy Compared
He & She MD starts at $149/mo (12-month supply) and offers injection, topical cream & nasal spray, while RNK Health starts at $129/mo with injection, nasal & oral liposomal. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared
He & She MD
The only major NAD+ provider that lets you pick your format — injection, cream, or nasal spray — without paying a cent more for the privilege.
Visit He & She MD →
RNK Health
From $129/mo. Longevity protocols with coaching. Injection, nasal, or oral.
Visit RNK Health →| Feature | He & She MD | RNK Health |
|---|---|---|
| Editorial score | 9.92 / 10 | 9.05 / 10 |
| Starting price | $149/mo (12-month supply) | $129/mo |
| Renewal / ongoing | Flat $149/mo across every format | $129/mo |
| Delivery formats | Injection, topical cream & nasal spray | Injection, nasal & oral liposomal |
| Dose strengths | Supplied as a 12-month course | Clinician-titrated |
| Shipping | Free expedited | Included (~48h) |
| Membership / fees | None — no membership cost | Subscription includes care |
| Guarantee | — | — |
| Best for | People who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost | Optimizing performance, healthy aging, and longevity |
Where He & She MD stands out
- + No required membership fee
- + Higher editorial score (9.92 vs 9.05)
Where RNK Health stands out
- + Lower entry price — $129/mo
- + More delivery formats — injection, nasal & oral liposomal
Pros & cons, side by side
He & She MD
Pros
- + Three delivery formats — subcutaneous injection, topical cream, and nasal spray
- + Two needle-free options (cream and nasal spray), rare in this market
- + One flat $149/mo price across every format, locked on a 12-month supply
- + No membership fee, no hidden costs, and HSA/FSA cards accepted
- + 5-minute intake quiz reviewed by a licensed U.S. physician or DO
- + Unlimited provider messaging for as long as you are on the program
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − The $149/mo rate is locked on a 12-month supply ($1,788/yr)
RNK Health
Pros
- + Best for performance-focused users
- + Science-backed longevity approach
- + Coaching and wellness metrics included
Cons
- − No money-back guarantee once medication ships
The verdict: He & She MD vs RNK Health
In our editorial ranking, He & She MD places higher (#1 vs #14), making it the default pick for most readers — it's best for people who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost. That said, RNK Health is the stronger choice for optimizing performance, healthy aging, and longevity. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.