He & She MD vs Sprout Health: NAD+ Therapy Compared
He & She MD starts at $149/mo (12-month supply) and offers injection, topical cream & nasal spray, while Sprout Health starts at $149 first month with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared
He & She MD
The only major NAD+ provider that lets you pick your format — injection, cream, or nasal spray — without paying a cent more for the privilege.
Visit He & She MD →
Sprout Health
Transparent dosing — 1,000mg/5mL twice weekly. $149 first month, then $240 every 4 weeks.
Visit Sprout Health →| Feature | He & She MD | Sprout Health |
|---|---|---|
| Editorial score | 9.92 / 10 | 8.90 / 10 |
| Starting price | $149/mo (12-month supply) | $149 first month |
| Renewal / ongoing | Flat $149/mo across every format | $240 every 4 weeks |
| Delivery formats | Injection, topical cream & nasal spray | Injection |
| Dose strengths | Supplied as a 12-month course | 1,000mg/5mL, twice weekly |
| Shipping | Free expedited | Free & discreet |
| Membership / fees | None — no membership cost | None |
| Guarantee | — | No charge if clinician declines |
| Best for | People who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost | People who want full upfront disclosure of dose, frequency, and renewal price before starting |
Where He & She MD stands out
- + More delivery formats — injection, topical cream & nasal spray
- + Higher editorial score (9.92 vs 8.90)
Where Sprout Health stands out
- + Backed by a no charge if clinician declines
Pros & cons, side by side
He & She MD
Pros
- + Three delivery formats — subcutaneous injection, topical cream, and nasal spray
- + Two needle-free options (cream and nasal spray), rare in this market
- + One flat $149/mo price across every format, locked on a 12-month supply
- + No membership fee, no hidden costs, and HSA/FSA cards accepted
- + 5-minute intake quiz reviewed by a licensed U.S. physician or DO
- + Unlimited provider messaging for as long as you are on the program
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − The $149/mo rate is locked on a 12-month supply ($1,788/yr)
Sprout Health
Pros
- + Fully discloses vial strength, dosing frequency, and renewal price
- + Free consultation, injection kit, and discreet shipping included
- + No hidden fees and cancel anytime
Cons
- − Renews at a higher rate after the first month
- − Injection-only; not available in AR, KS, or NM
The verdict: He & She MD vs Sprout Health
In our editorial ranking, He & She MD places higher (#1 vs #16), making it the default pick for most readers — it's best for people who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost. That said, Sprout Health is the stronger choice for people who want full upfront disclosure of dose, frequency, and renewal price before starting. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.