He & She MD vs Telos: NAD+ Therapy Compared
He & She MD starts at $149/mo (12-month supply) and offers injection, topical cream & nasal spray, while Telos starts at nasal $49 first month (12-mo plan) with nasal spray. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
- Physician-Prescribed Only
- 32 Providers Compared
He & She MD
The only major NAD+ provider that lets you pick your format — injection, cream, or nasal spray — without paying a cent more for the privilege.
Visit He & She MD →
Telos
Needle-free NAD+ nasal treatment from $49 for the first month. Nasal spray — not injections.
Visit Telos →| Feature | He & She MD | Telos |
|---|---|---|
| Editorial score | 9.92 / 10 | 8.10 / 10 |
| Starting price | $149/mo (12-month supply) | Nasal $49 first month (12-mo plan) |
| Renewal / ongoing | Flat $149/mo across every format | Shown during intake |
| Delivery formats | Injection, topical cream & nasal spray | Nasal spray |
| Dose strengths | Supplied as a 12-month course | Not disclosed |
| Shipping | Free expedited | Not stated |
| Membership / fees | None — no membership cost | None |
| Guarantee | — | — |
| Best for | People who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost | People who prefer a needle-free nasal NAD+ option at a low entry price |
Where He & She MD stands out
- + More delivery formats — injection, topical cream & nasal spray
- + Higher editorial score (9.92 vs 8.10)
Where Telos stands out
- + Lower entry price — Nasal $49 first month (12-mo plan)
Pros & cons, side by side
He & She MD
Pros
- + Three delivery formats — subcutaneous injection, topical cream, and nasal spray
- + Two needle-free options (cream and nasal spray), rare in this market
- + One flat $149/mo price across every format, locked on a 12-month supply
- + No membership fee, no hidden costs, and HSA/FSA cards accepted
- + 5-minute intake quiz reviewed by a licensed U.S. physician or DO
- + Unlimited provider messaging for as long as you are on the program
Cons
- − Compounded NAD+ — not an FDA-approved finished drug product
- − The $149/mo rate is locked on a 12-month supply ($1,788/yr)
Telos
Pros
- + Needle-free nasal delivery
- + Low $49 first-month entry price
- + Fully online process
Cons
- − Lowest pricing may require a 12-month plan
- − Nasal spray only — no injections
The verdict: He & She MD vs Telos
In our editorial ranking, He & She MD places higher (#1 vs #24), making it the default pick for most readers — it's best for people who want injection, cream, or nasal spray at one identical price, so the decision is about comfort rather than cost. That said, Telos is the stronger choice for people who prefer a needle-free nasal NAD+ option at a low entry price. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.